The Molecular Mechanism of Natural Products Activating Wnt/Beta-Catenin Signaling Pathway for Improving Hair Loss
November 2022
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research Sexual Dysfunction in Subjects Treated with Inhibitors of 5α-Reductase for Benign Prostatic Hyperplasia: A Comprehensive Review and Meta-Analysis
Men taking 5α-reductase inhibitors for enlarged prostate have a higher chance of experiencing reduced sexual desire and erectile dysfunction.
research Medications Most Commonly Associated With Erectile Dysfunction: Evaluation Of The Food And Drug Administration National Pharmacovigilance Database
research Identification of Hair Growth Promoting Components in the Kernels of Prunus Mira Koehne and Their Mechanism of Action
Prunus mira kernels contain components that can promote hair growth in mice.
research Hair Follicle Morphogenesis During Embryogenesis, Neogenesis, and Organogenesis
The document concludes that understanding adult stem cells and their environments can help improve skin regeneration in the future.
research Phytochemical Constitution, Anti-Inflammation, Anti-Androgen, and Hair Growth-Promoting Potential of Shallot (Allium Ascalonicum L.) Extract
research Alpinetin Promotes Hair Regeneration via Activating Hair Follicle Stem Cells
Alpinetin helps grow hair by turning on hair stem cells and is safe for use.
research Morphogenesis, Growth Cycle, and Molecular Regulation of Hair Follicles
Hair growth and health are influenced by factors like age, environment, and nutrition, and are controlled by various molecular pathways. Red light can promote hair growth, and understanding these processes can help treat hair-related diseases.
research 5-Bromo-3,4-Dihydroxybenzaldehyde Promotes Hair Growth Through Activation of Wnt/β-Catenin and Autophagy Pathways and Inhibition of TGF-β Pathways in Dermal Papilla Cells
5-Bromo-3,4-dihydroxybenzaldehyde could potentially help hair growth by activating certain cell pathways and inhibiting others.
research Effects of Watercress Extract Fraction on R-Spondin 1-Mediated Growth of Human Hair
Watercress extract helps increase hair growth and thickness by blocking hair loss factors.
research Hair-Growth Promoting Effect and Anti-Inflammatory Mechanism of Ginkgo Biloba Polysaccharides
Ginkgo biloba polysaccharides may reduce inflammation and promote hair growth in mice with hair loss.
research Tissue Engineering and Regeneration of the Human Hair Follicle in Androgenetic Alopecia: Literature Review
Tissue engineering could be a future solution for hair loss, but it's currently expensive, complex, and hard to apply in real-world treatments.
research Modulation of Hair Growth Promoting Effect by Natural Products
Natural products like plant extracts can help promote hair growth and could be used to treat hair loss.
research Hair Growth-Promoting Effect of Resveratrol in Mice, Human Hair Follicles, and Dermal Papilla Cells
Resveratrol may help hair grow, but more research is needed.
research A Systematic Summary of Survival and Death Signaling During the Life of Hair Follicle Stem Cells
The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.
research Hair Growth Stimulation Effect of Centipeda Minima Extract: Identification of Active Compounds and Anagen-Activating Signaling Pathways
Centipeda minima extract helps hair grow by activating important growth signals and could be a promising hair loss treatment.
research Exosomes Derived from Fisetin-Treated Keratinocytes Mediate Hair Growth Promotion
Fisetin in fruits and vegetables helps hair growth in mice.
research Activation of Hair Cell Growth Factors by Linoleic Acid in Malva Verticillata Seed
Linoleic acid from Malva verticillata seeds may help treat hair loss by promoting hair cell growth and blocking baldness signals.
research Myristoleic Acid Promotes Anagen Signaling by Autophagy Through Activating Wnt/β-Catenin and ERK Pathways in Dermal Papilla Cells
Myristoleic acid helps hair growth by boosting cell growth and recycling processes in hair follicle cells.
research Functional Hair Follicle Regeneration: An Updated Review
Hair follicle regeneration possible, more research needed.
research Efficacy of Cetirizine 1% Versus Minoxidil 5% Topical Solution in the Treatment of Male Alopecia: A Randomized, Single-Blind Controlled Study
research Fisetin Promotes Hair Growth by Augmenting TERT Expression
Fisetin, a type of polyphenol, may help hair grow by increasing certain protein activities in cells.
research Hair Growth Activity of Three Plants of the Polynesian Cosmetopoeia and Their Regulatory Effect on Dermal Papilla Cells
Extracts from three Polynesian plants were found to promote hair growth by affecting cell growth and gene expression related to hair.
research Quercitrin Stimulates Hair Growth with Enhanced Expression of Growth Factors via Activation of MAPK/CREB Signaling Pathway
Quercitrin may help treat hair loss by promoting hair growth and improving cell health.
research Study on the Chemical Constituents of Nut Oil from Prunus Mira Koehne and the Mechanism of Promoting Hair Growth
Prunus mira nut oil helps hair grow by affecting the Wnt/β-catenin signaling pathway.
research Targeting Wnt/β-Catenin Pathway for Developing Therapies for Hair Loss
Activating the Wnt/β-catenin pathway could lead to new hair loss treatments.
research A Randomized, Single-Blinded, Vehicle-Controlled Study of a Topical Active Blend in the Treatment of Androgenetic Alopecia
Redenyl lotion effectively promotes hair growth and improves quality of life for androgenetic alopecia patients.
research Polygonum Multiflorum Extract Supports Hair Growth by Elongating Anagen Phase and Abrogating the Effect of Androgen in Cultured Human Dermal Papilla Cells
Polygonum multiflorum extract helps hair grow longer and fights the effects of hormones that cause hair loss.
research Macrophage-Derived Extracellular Vesicle Promotes Hair Growth
Special cell particles from macrophages can help hair grow.
research A Review of the Treatment of Male Pattern Hair Loss
Finasteride and minoxidil work best together for hair loss.
research Protective Role of Nutritional Plants Containing Flavonoids in Hair Follicle Disruption: A Review
Some plants with flavonoids may help treat hair loss and promote hair growth.
research Maintaining Hair Inductivity in Human Dermal Papilla Cells: A Review of Effective Methods
The review concluded that keeping the hair-growing ability of human dermal papilla cells is key for hair development and growth.
research Deciphering the Molecular Morphology of the Human Hair Cycle: Wnt Signalling During the Telogen–Anagen Transformation
Wnt signaling is important for the change from the resting phase to the growth phase in human hair cycles.
research Ginkgolide B and Bilobalide Promote Growth and Increase β-Catenin Expression in Hair Follicle Dermal Papilla Cells of American Minks
Ginkgolide B and bilobalide help mink hair grow by making skin cells healthier and boosting a key growth protein.
research The Balance of BMP6 and WNT10B Regulates the Telogen-Anagen Transition of Hair Follicles
BMP6 and Wnt10b control whether hair follicles are resting or growing.
research Dickkopf-1 Expression in Androgenetic Alopecia and Alopecia Areata in Male Patients
DKK-1 gene linked to hair loss in AGA and AA patients; more research needed for potential therapy.
research Medicinal Plants for the Treatment of Hair Loss and the Suggested Mechanisms
Some medicinal plants may treat hair loss with fewer side effects.
research Suppression of Wnt/β-Catenin Signaling by EGF Receptor Is Required for Hair Follicle Development
Blocking Wnt/β-catenin signaling with EGF receptor is necessary for proper hair growth.
research Review of Hair Follicle Dermal Papilla Cells as In Vitro Screening Model for Hair Growth
Dermal Papilla cells are a promising tool for evaluating hair growth treatments.
research Morroniside Regulates Hair Growth and Cycle Transition via Activation of the Wnt/β-Catenin Signaling Pathway
Morroniside may help hair grow and stay in its growth phase by affecting certain cell signals.
research Costunolide Promotes the Proliferation of Human Hair Follicle Dermal Papilla Cells and Induces Hair Growth in C57BL/6 Mice
Costunolide helps human hair cells grow and can stimulate hair growth in mice.
research Androgen Modulation of Wnt/β-Catenin Signaling in Androgenetic Alopecia
Androgens may block hair growth signals, targeting this could treat hair loss.
research Baicalin Increases Hair Follicle Development by Enhancing Canonical Wnt/β-Catenin Signaling and Activating Dermal Papilla Cells in Mice
Baicalin helps hair growth by activating specific cell signals and pathways.
research Epidermal E-Cadherin Dependent β-Catenin Pathway Is Phytochemical Inducible and Accelerates Anagen Hair Cycling
A form of vitamin E promotes hair growth by activating a specific skin pathway.
research Concise Review: Wnt Signaling Pathways in Skin Development and Epidermal Stem Cells
Wnt signaling is crucial for skin development and hair growth.
research Hair Regenerative Mechanisms of Red Ginseng Oil and Its Major Components in the Testosterone-Induced Delay of Anagen Entry in C57BL/6 Mice
Red ginseng oil and its components help promote hair regrowth and could treat hair loss.
research Beta-Catenin Is Involved in Oleanolic Acid-Dependent Promotion of Proliferation in Human Hair Matrix Cells in an In Vitro Organ Culture Model
Oleanolic acid promotes hair growth by increasing cell proliferation through the Wnt/β-catenin pathway.
research Effect of Sinapic Acid on Hair Growth Promotion in Human Hair Follicle Dermal Papilla Cells via Akt Activation
Sinapic acid may help hair growth by activating a specific cell pathway.
research Androgens Modify Wnt Agonists/Antagonists Expression Balance in Dermal Papilla Cells Preventing Hair Follicle Stem Cell Differentiation in Androgenetic Alopecia
Androgens prevent hair growth by changing Wnt signals in cells.
research 3-Deoxysappanchalcone Promotes Proliferation of Human Hair Follicle Dermal Papilla Cells and Hair Growth in C57BL/6 Mice by Modulating WNT/β-Catenin and STAT Signaling
3-Deoxysappanchalcone helps human hair cells grow and stimulates hair growth in mice by affecting certain cell signaling pathways.
research Wnt5a Suppresses β-Catenin Signaling During Hair Follicle Regeneration
Wnt5a slows down hair growth by blocking a specific pathway during hair regeneration.
research The Diagnosis and Treatment of Hair and Scalp Diseases
Hair loss requires customized treatments based on its various causes and types.
research Epidermal Growth Factor Promotes Proliferation and Migration of Follicular Outer Root Sheath Cells via Wnt/β-Catenin Signaling
Epidermal Growth Factor helps hair follicle cells grow and move by activating a specific cell signaling pathway.
research Malva Verticillata Seed Extracts Upregulate the Wnt Pathway in Human Dermal Papilla Cells
Malva verticillata seed extract might help treat hair loss by activating hair growth signals in skin cells.
research Analysis of Changes in MicroRNA Expression Profiles in Response to the Troxerutin-Mediated Antioxidant Effect in Human Dermal Papilla Cells
Troxerutin helps protect skin cells from oxidative stress and may be good for treating hair loss.
research Fibroblast Growth Factors Stimulate Hair Growth Through Beta-Catenin and Shh Expression in C57BL/6 Mice
Certain growth factors can promote hair growth in mice by activating hair growth-related proteins.
research Baicalin, A Flavonoid, Affects The Activity Of Human Dermal Papilla Cells And Promotes Anagen Induction In Mice
Baicalin helps hair grow by boosting certain cell activities and speeding up hair cycle in mice.
research Treatment of MSCs with Wnt1a-Conditioned Medium Activates DP Cells and Promotes Hair Follicle Regrowth
Wnt1a-conditioned medium from stem cells helps activate cells important for hair growth and can promote hair regrowth.
research Topical Valproic Acid Increases Hair Count in Male Patients with Androgenetic Alopecia: A Randomized, Comparative, Clinical Feasibility Study Using Phototrichogram Analysis
Valproic acid increases hair count in men with hair loss.
research CCN2 Modulates Hair Follicle Cycling in Mice
The protein CCN2 controls hair growth by affecting hair follicle formation and stem cell activity in mice.
research Valproic Acid Promotes Human Hair Growth in In Vitro Culture Model
Valproic acid may help hair grow and could be a safe treatment for hair loss.
research Hair Growth-Promoting Activity of Hot Water Extract of Thuja Orientalis
Thuja orientalis hot water extract may help hair grow by starting the growth phase and improving hair follicle development.
research Adenovirus-Mediated Wnt10b Overexpression Induces Hair Follicle Regeneration
Wnt10b overexpression can regenerate hair follicles, possibly helping treat hair loss and alopecia.
research Adenovirus-Mediated Wnt5a Expression Inhibits the Telogen-To-Anagen Transition of Hair Follicles in Mice
Increasing Wnt5a in mice skin delays hair growth but doesn't stop it.
research Epithelial Wnt Ligand Secretion Is Required for Adult Hair Follicle Growth and Regeneration
Wnt ligands are crucial for hair growth and repair.
research Hair Growth-Promoting Effect of Aconiti Ciliare Tuber Extract Mediated by the Activation of Wnt/β-Catenin Signaling
Aconiti Ciliare Tuber extract may help hair grow by activating a specific cell signaling pathway.
research Hair Follicle Stem Cell Differentiation Is Inhibited Through Cross-Talk Between Wnt/β-Catenin and Androgen Signaling in Dermal Papilla Cells From Patients With Androgenetic Alopecia
Androgens block hair growth by disrupting cell signals; targeting GSK-3 may help treat hair loss.
research Minoxidil Use in Dermatology, Side Effects, and Recent Patents
Minoxidil treats hair loss, promotes growth, has side effects, and has recent patents.
research Valproic Acid Induces Hair Regeneration in Murine Model and Activates Alkaline Phosphatase Activity in Human Dermal Papilla Cells
Valproic Acid helps regrow hair in mice and activates a hair growth marker in human cells.
research Persistent Sexual Side Effects of Finasteride for Male Pattern Hair Loss
Finasteride for hair loss can cause long-lasting sexual side effects like low libido and erectile dysfunction.
research Beta-Catenin Activity in the Dermal Papilla Regulates Morphogenesis and Regeneration of Hair
β-catenin in the dermal papilla is crucial for normal hair growth and repair.
research Keratinocyte Growth Inhibition Through the Modification of Wnt Signaling by Androgen in Balding Dermal Papilla Cells
Androgens slow hair growth by altering Wnt signaling in balding cells.
research Human Hair Growth Enhancement In Vitro By Green Tea Epigallocatechin-3-Gallate (EGCG)
Green tea component EGCG could potentially promote human hair growth.
research Molecular Control of Epithelial-Mesenchymal Interactions During Hair Follicle Cycling
Epithelial-mesenchymal interactions control hair growth cycles through specific molecular signals.
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research Maintenance of Optimized Hair Growth from Viable Terminal Scalp Hair Follicles at Baseline with Oral Finasteride in Male Pattern Hair Loss and First Evidence of a Drug Dependency and a Post-Finasteride Rebound Effect
Finasteride helps hair growth but stopping it causes faster hair loss.
research Hair-Growth Potential of Ginseng and Its Major Metabolites: A Review on Its Molecular Mechanisms
Ginseng and its compounds may help hair growth and prevent hair loss, but more human trials are needed to confirm this.
research Multi-Therapies in Androgenetic Alopecia: Review and Clinical Experiences
Multiple treatments work best for hair loss.
research Androgenetic Alopecia and Its Remedies: A Review
research Low-Level Laser Therapy for Treatment of Hair Loss
Low-Level Laser Therapy is effective and safe for hair growth with minimal side effects.
research A Study on Effects of Water-Soluble Minoxidil on Hair Growth in C57BL/6 Mice
research Natural Scalp Hair Regression in Preclinical Stages of Male Androgenetic Alopecia and Its Reversal by Finasteride
Finasteride reverses early hair loss and promotes growth.
research Androgenetic Alopecia: Pathogenesis and Potential for Therapy
Hair loss needs more research for better treatments.