Study on the Chemical Constituents of Nut Oil from Prunus Mira Koehne and the Mechanism of Promoting Hair Growth

    August 2020 in “ Journal of ethnopharmacology
    You Zhou, Guangmin Tang, Xiaoli Li, Weijun Sun, Yuan Liang, Deqiang Gan, Guangli Liu, Wen-Jie Song, Zhang Wang
    TLDR Prunus mira nut oil helps hair grow by affecting the Wnt/β-catenin signaling pathway.
    The study analyzed the chemical constituents of nut oil from Prunus mira and its mechanism in promoting hair growth. It identified key components such as vitamin E, β-sitosterol, α-tocopherol, oleic acid, and linoleic acid. Using a depilated mouse model, the study found that P. mira nut oil, in doses ranging from 15.06 to 60.26 mg/cm²/day, effectively promoted hair growth. The research suggested that the nut oil's mechanism involved the Wnt/β-catenin signaling pathway, which is crucial for hair follicle regeneration. This provided a potential alternative to existing hair growth treatments with fewer side effects.
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