6-O Glucose Linoleate Supports In Vitro Human Hair Growth and Lipid Synthesis

The study investigated the effects of 6-O-linoleyl-d-glucose (6-O-GL) on human hair growth and lipid synthesis in vitro. The researchers found that 6-O-GL was stable and resistant to oxidative degradation, and it was effectively absorbed and metabolized by hair follicles into various lipids, including neutral lipids, ceramides, and polar lipids. Importantly, 6-O-GL supported hair follicle growth and survival even in the absence of glucose and linoleic acid, indicating its role as a bi-functional nutrient that ensures both the quality and production of hair fibers.