6-O Glucose Linoleate Supports In Vitro Human Hair Growth and Lipid Synthesis

March 2007 in “ International Journal of Cosmetic Science ”

Philippe Vingler, Brigitte Gautier, Maria Dalko, Roger Rozot, O Gaillard, J Michelet, Bruno Bernard

6-O-linoleyl-d-glucose hair growth lipid synthesis hair follicles neutral lipids ceramides polar lipids glucose linoleic acid

TLDR 6-O glucose linoleate helps human hair grow and produce lipids.

The study investigated the effects of 6-O-linoleyl-d-glucose (6-O-GL) on human hair growth and lipid synthesis in vitro. The researchers found that 6-O-GL was stable and resistant to oxidative degradation, and it was effectively absorbed and metabolized by hair follicles into various lipids, including neutral lipids, ceramides, and polar lipids. Importantly, 6-O-GL supported hair follicle growth and survival even in the absence of glucose and linoleic acid, indicating its role as a bi-functional nutrient that ensures both the quality and production of hair fibers.

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Research cited in this study

5 / 5 results

research Characterization of the Lipid Composition at the Proximal Root Regions of Human Hair

41 citations , May 2005 in “International Journal of Cosmetic Science”

Human hair contains various lipids that vary among individuals and help protect the hair.

research Hair Keratin Pattern in Human Hair Follicles Grown In Vitro

29 citations , April 2003 in “Experimental dermatology”

Human hair follicles grown in vitro maintain normal keratin patterns and structure.

research Epithelial Barrier Function: Assembly and Structural Features of the Cornified Cell Envelope

425 citations , August 2002 in “BioEssays”

The cornified cell envelope forms a protective barrier in skin and hair, using specific proteins and lipids to maintain effectiveness.

research Hair Biology: An Update

11 citations , February 2002 in “International Journal of Cosmetic Science”

Recent findings show that hair growth and color are controlled by a complex network of signals in the hair follicle.

research On the Use of Micro-Imager to Directly Visualize Drug Distribution in Human Skin

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