Study of the Keratinization Process in Human Hair Follicle by X-Ray Microdiffraction
July 2000
in “
PubMed
”
Studysummary This study found no structural differences between in vitro and in vivo grown hair, with keratinization and organization of keratin being comparable in both settings.
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The study utilized synchrotron X-ray micro-diffraction to examine the keratinization process in human hair follicles. It was found that the molecular organization of keratin, specifically the formation of alpha-helices, was completed within the follicle, while the supramolecular organization and filament structure appeared outside the follicle. The research indicated no structural differences between in vitro and in vivo grown hair, as both exhibited the same structure, and no variations were observed in the transition zone between in vivo and in vitro conditions.
