TLDR Hair structure forms the same way inside and outside the body.
The study used synchrotron X-ray micro-diffraction to examine the keratinization process in human hair follicles, revealing that molecular organization, specifically the formation of alpha-helices, was completed inside the follicle, while supramolecular organization and filament structure appeared outside the follicle. Comparisons between in vitro and in vivo grown hair showed no structural differences, indicating that the keratinization process was consistent regardless of the growth environment.
19 citations
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April 2015 in “International Journal of Molecular Sciences” The research identified genes and pathways important for sheep wool growth and shedding.
73 citations
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May 2009 in “Proceedings of the National Academy of Sciences” Disrupting the Sox21 gene in mice causes hair loss and regrowth cycles.
January 2006 in “Chinese Journal of Dermatology” Mesenchymal cells are essential for hair follicle stem cell growth.
276 citations
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January 2005 in “International review of cytology” More research is needed to understand how hair keratins work and their role in hair disorders.
199 citations
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January 2004 in “The International Journal of Developmental Biology” Hair follicle growth and development are controlled by specific genes and molecular signals.
28 citations
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July 2000 in “PubMed” Hair structure forms the same way inside and outside the body.
6 citations
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October 1988 in “Clinics in Dermatology” The molecular details of hair growth are not well understood.
34 citations
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August 1966 in “Experimental cell research” Keratin fibrils in hair form and stop growing at specific points in the follicle.