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research In Vitro Assembly and Structure of Trichocyte Keratin Intermediate Filaments

91 citations , December 2000 in “The journal of cell biology/The Journal of cell biology”

This study reports that expressed mouse type Ia and type IIa trichocyte keratins were successfully assembled into intermediate filaments in vitro, while also suggesting that disulfide bond cross linking enhances their stability.

research Structure of intermediate filament assembly in hair deduced from hydration studies using small-angle neutron scattering

9 citations , April 2019 in “Journal of structural biology”

This study found that coconut oil impedes hair hydration more effectively than soybean oil by penetrating deeper, and suggested a new model for intermediate filament assembly in hair.

research The role of disulfide bond formation in the structural transition observed in the intermediate filaments of developing hair

39 citations , June 2012 in “Journal of Structural Biology”

Disulfide bonds are crucial for hair structure during keratinization.

research The structure of human trichohyalin : potential multiple roles as a functional ef-hand-like calcium-binding protein, a cornified cell envelope precursor, and an intermediate filament-associated (cross-linking) protein

2 citations , January 1993

This study found that human trichohyalin has a unique protein sequence potentially contributing to at least three important functions in hair follicle and epidermal cells.

research From structural resilience to cell specification — Intermediate filaments as regulators of cell fate

9 citations , November 2020 in “The FASEB journal”

This review discusses the role of intermediate filaments in cell signaling and differentiation, emphasizing their impact on stem cell function, development, and disease, but reports no new clinical results.

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community Sebaceous filaments / blackheads on scalp - are they a cause of MPB or a symptom?

in Research/Science 1 upvotes 1 month ago

Sebaceous filaments or blackheads on the scalp are not a cause of hair loss; it's more likely due to hormonal factors, particularly in androgen-sensitive areas like the temples and crown. The user is using topical finasteride, minoxidil, and tretinoin for treatment.

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