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research Structure of Intermediate Filament Assembly in Hair Deduced from Hydration Studies Using Small-Angle Neutron Scattering

9 citations , April 2019 in “Journal of structural biology”

Hair's internal fibers are arranged in a pattern that doesn't let much water in, and treatments like oils and heat change how much water hair can absorb.

research Complete Structure of an Epithelial Keratin Dimer: Implications for Intermediate Filament Assembly

42 citations , July 2015 in “PLoS ONE”

The study revealed the detailed structure of a keratin dimer, aiding understanding of how intermediate filament proteins function.

research The Intermediate Filament Architecture as Determined by X-Ray Diffraction Modeling of Hard Alpha-Keratin

66 citations , June 2004 in “Biophysical Journal”

Hard α-keratin in hair has a unique, nonordered structure, different from other fibers.

research De Novo Filament Formation by Human Hair Keratins K85 and K35 Follows a Filament Development Pattern Distinct from Cytokeratin Filament Networks

2 citations , February 2021 in “FEBS open bio”

Human hair keratins K85 and K35 create unique filament patterns important for early hair formation.

research Study of the Keratinization Process in Human Hair Follicle by X-Ray Microdiffraction

28 citations , July 2000 in “PubMed”

Hair structure forms the same way inside and outside the body.

View more "filament structure" in research →

Community Join

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community Common hair-loss drug consistently associated with higher rates of psychiatric harm

in Research/Science 183 upvotes 2 months ago

Finasteride and dutasteride can cause psychiatric side effects like depression and suicidal thoughts in some users, especially those with a history of mental health issues. While some users experience positive hair growth results, others face severe psychological effects, raising concerns about their safety and the need for careful monitoring.

community Nov 2023 to today. 1mg finasteride daily since Feb 2024. Considering moving to Dutasteride based on the anecdotes I see on this sub and would like input.

in Progress Pictures 260 upvotes 11 months ago

A 30-year-old is using 1mg finasteride daily and 5% minoxidil inconsistently for hair regrowth, noticing recent progress and considering switching to dutasteride. Users advise continuing the current regimen for at least two years before considering dutasteride, as finasteride and minoxidil are showing positive results.

community New baby hairs are popping out. Question though: what are these black dots on hairline? Clogged pores?

in Finasteride/Dutasteride 39 upvotes 5 months ago

The user is experiencing new hair growth after using oral dutasteride, topical minoxidil, and microneedling, but is concerned about black dots on the hairline, which might be clogged pores or dormant follicles. The user previously used a topical minoxidil/finasteride spray and had good results, despite a shedding phase after switching treatments.

community Not all generic medications are made equal. Some work great, some weaker, and some are dangerous. What Pharmaceutical makes your current/past generic Finasteride?

in Finasteride/Dutasteride 6 upvotes 4 years ago

The conversation discusses the variability in effectiveness and safety of generic finasteride from different manufacturers, with some generics potentially containing impurities. Users shared their experiences with various brands, questioning if different brands affect hair loss treatment outcomes.