Synthesis and Cross-Linking in the Structure and Growth of Hair Keratins
October 1988
in “
Clinics in Dermatology
”
New to Keratin? There is a guide in the encyclopedia. Read the guide → Studysummary This article reviews gaps in our understanding of molecular events in hair follicle growth, focusing on keratin synthesis and protein oxidation, but reports no new findings.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
The document discussed the biochemical mechanisms involved in hair growth, highlighting the limited understanding of molecular events within the hair follicle at the time. It described the process of hair cell migration from the bulb region, taking approximately 5 days to become keratinized. During keratin synthesis, the -SH content in proteins decreased rapidly due to oxidation to disulfide bonds, reaching an oxidized state within 6-12 hours. Despite extensive literature, the hair follicle remained a "black box" in terms of detailed molecular knowledge.
