TLDR Transamidases help form strong crosslinks in hair proteins, crucial for hair strength.
The 1972 study investigated the formation of iε-(γ-glutamyl)lysine crosslinks in hair proteins and the role of transamidases in hair follicles, focusing on the enzymatic processes crucial for hair's structural integrity. The research provided insights into the biochemical mechanisms of hair protein crosslinking, contributing to the understanding of hair biology and potential implications for hair growth and hair loss treatments.
49 citations
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January 1972 in “Biochimica et Biophysica Acta (BBA) - Protein Structure” 125 citations
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February 1971 in “Biochemistry” Specific cross-linkages help make hair proteins stable and strong.
82 citations
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November 1959 in “Annals of the New York Academy of Sciences”
125 citations
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February 1971 in “Biochemistry” Specific cross-linkages help make hair proteins stable and strong.
122 citations
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January 2006 in “Molecular & Cellular Proteomics” Human hair contains many proteins, with some being highly abundant and modified.
49 citations
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May 1974 in “Biochimica et Biophysica Acta (BBA) - Protein Structure” Transamidases are present in the epidermis but their exact role is unclear.
30 citations
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August 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” TGase 3 helps build hair structure by forming strong bonds between proteins.
135 citations
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October 1997 in “Journal of biological chemistry/The Journal of biological chemistry” Trichohyalin is modified by enzymes to form strong structures in hair cells.
