TLDR Transamidases help form strong crosslinks in hair proteins, crucial for hair strength.
The 1972 study investigated the formation of iε-(γ-glutamyl)lysine crosslinks in hair proteins and the role of transamidases in hair follicles, focusing on the enzymatic processes crucial for hair's structural integrity. The research provided insights into the biochemical mechanisms of hair protein crosslinking, contributing to the understanding of hair biology and potential implications for hair growth and hair loss treatments.
82 citations,
November 1959 in “Annals of the New York Academy of Sciences”
30 citations,
August 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” TGase 3 helps build hair structure by forming strong bonds between proteins.
135 citations,
October 1997 in “Journal of biological chemistry/The Journal of biological chemistry” Trichohyalin is modified by enzymes to form strong structures in hair cells.
375 citations,
June 2013 in “Biochimica et biophysica acta. Molecular cell research” Cornification is how skin cells die to form the protective outer layer of skin, hair, and nails.
99 citations,
May 1998 in “Journal of biological chemistry/The Journal of biological chemistry” Small proline-rich proteins and trichohyalin help make epithelial tissues tougher and more flexible.
February 2024 in “Epigenomes” Epigenetic mechanisms control skin development by regulating gene expression.
