The Fate of Trichohyalin

    October 1997 in “ Journal of biological chemistry/˜The œJournal of biological chemistry ”
    Edit Tarcsa, Lyuben N. Marekov, Jeanne M. Andreoli … Peter M. Steinert
    Studysummary This study suggests that trichohyalin is modified by peptidyl-arginine deiminase before being cross-linked by TGase 3, allowing the formation of rigid structures in hair follicle cells.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 15

    1. Existence of Trichohyalin-Keratohyalin Hybrid Granules: Co-Localization of Two Major Intermediate Filament-Associated Proteins in Non-Follicular Epithelia Differentiation · 1994
    2. Apoptosis in Human Skin Development: Morphogenesis, Periderm, and Stem Cells Developmental dynamics · 1994
    3. Trichohyalin: A Structural Protein of Hair, Tongue, Nail, and Epidermis ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1993
    4. The Structure of Human Trichohyalin: Potential Multiple Roles as a Functional EF-Hand-Like Calcium-Binding Protein, a Cornified Cell Envelope Precursor, and an Intermediate Filament-Associated (Cross-Linking) Protein Journal of Biological Chemistry · 1993
    5. Analysis of the Sheep Trichohyalin Gene: Potential Structural and Calcium-Binding Roles of Trichohyalin in the Hair Follicle The Journal of Cell Biology · 1993
    6. Trichohyalin: Purification from Porcine Tongue Epithelium and Characterization of the Native Protein Journal of Investigative Dermatology · 1992
    7. Trichohyalin: Presence in the Granular Layer and Stratum Corneum of Normal Human Epidermis ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1991
    8. Patterns of Expression of Trichocytic and Epithelial Cytokeratins in Mammalian Tissues: Human and Bovine Hair Follicles Differentiation · 1988
    9. Trichohyalin, an Intermediate Filament-Associated Protein of the Hair Follicle ˜The œjournal of cell biology/˜The œJournal of cell biology · 1986
    10. Structural Features of the Alpha-Type Filaments of the Inner Root Sheath Cells of the Guinea Pig Hair Follicle Biochemistry · 1978
    11. The Origin of Citrulline-Containing Proteins in the Hair Follicle and the Chemical Nature of Trichohyalin, an Intracellular Precursor Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · 1977
    12. Formation of the Iε-(γ-Glutamyl)Lysine Crosslink in Hair Proteins: Investigation of Transamidases in Hair Follicles Biochemistry · 1972
    13. Transglutaminase from Hair Follicle of Guinea Pig Proceedings of the National Academy of Sciences · 1972
    14. Iε-(γ-Glutamyl) Lysine Cross-Linkage in Citrulline-Containing Protein Fractions From Hair Biochemistry · 1971
    15. The Localization And Significance Of Arginine And Citrulline In Proteins Of The Hair Follicle Journal of Histochemistry & Cytochemistry · 1963