Search

for
Search:

GlossaryPeptidylarginine Deiminase (PAD)

enzyme converting arginine in proteins to citrulline

Peptidylarginine Deiminase (PAD) is an enzyme that converts arginine residues in proteins into citrulline through a process called deimination or citrullination. This modification can affect protein function and is involved in various physiological processes, including the regulation of gene expression and the formation of hair. Dysregulation of PAD activity has been linked to autoimmune diseases and conditions like alopecia.

Related Terms

Learn

0 / 0 results

— no results

Research

5 / 1000+ results

research Molecular Cloning of Two Novel Types of Peptidylarginine Deiminase cDNAs from Retinoic Acid-Treated Culture of a Newborn Rat Keratinocyte Cell Line

39 citations , August 1998 in “FEBS Letters”

Two new enzymes, PAD-R11 and PAD-R4, were cloned and showed activity, with PAD-R11 resembling epidermal enzymes.

research The Fate of Trichohyalin

135 citations , October 1997 in “Journal of biological chemistry/The Journal of biological chemistry”

Trichohyalin is modified by enzymes to form strong structures in hair cells.

research Peripheral Arterial Disease: Diagnosis And Management

101 citations , August 2008 in “Mayo Clinic Proceedings”

PAD is common but often missed, needing lifestyle changes and medication for better outcomes.

research Isolation and Molecular Cloning of Epidermal and Hair Follicle-Specific Peptidylarginine Deiminase Type III from Rat

42 citations , May 1997 in “The Journal of Biochemistry”

PAD type III enzyme is specific to rat skin and hair follicles.

research Peptidylarginine Deiminase Isoforms Are Differentially Expressed in Anagen Hair Follicles and Other Human Skin Appendages

71 citations , June 2005 in “Journal of Investigative Dermatology”

PAD enzymes play a key role in hair growth and structure.

View more "pad" in research →

Community Join

5 / 68 results

community Back from the depths - 24M, big 3

in Progress Pictures 70 upvotes 3 years ago

A 24-year-old man saw hair loss improvement after 5 months using 1 mg finasteride daily, 5% minoxidil nightly, weekly microneedling with a Dr. Pen A6 at 1.5mm, daily biotin (at least 10,000 mcg), and using a shampoo for thinning hair every other day. He experienced no side effects and confirmed his health with bloodwork.

community When will FAK Inhibitors / Standford Hydrogel be on the market for hair transplants?

in Research/Science 9 upvotes 2 months ago

The conversation discusses the delay in bringing FAK inhibitors and Stanford's hydrogel to market for hair transplants, with a preference for FAK inhibitors over Verteporfin due to their superior potential in preventing scarring. The user expresses frustration over the slow progress and hopes for faster development by companies like FAKnostics.

community Microneedling : Questions regarding routine and sanitary

7 upvotes 7 years ago

The conversation discusses microneedling for hair regrowth, emphasizing the importance of disinfecting the scalp to avoid infections. It also mentions using minoxidil and castor oil in the treatment routine.

community My dermatologist didn't give me finasteride and instead gave me latanoprost and some cream

in Treatment 8 upvotes 4 years ago

User asked dermatologist for finasteride, received latanoprost and diprogenta cream instead. Others suggest latanoprost is expensive and not better than minoxidil, recommend trying another doctor for finasteride.

community 6 Months Update - 8000 Hair - Hair Transplant in Toronto

in Progress Pictures 752 upvotes 1 year ago

A user shared progress pictures of a hair transplant from Padra Clinic in Toronto, claiming 8000 hairs were transplanted for $4000 CAD. The post faced skepticism, with users questioning the results and clinic's credibility, while the user mentioned using zinc, biotin, and hair laser therapy for aftercare.

View more "pad" in community →