Transglutaminase-3 Enzyme: A Putative Actor in Human Hair Shaft Scaffolding?

    S. Thibaut, Nükhet Cavusoglu, E. De Becker … Bruno Bernard
    Studysummary This study suggests that TGase 3 may contribute to hair fiber scaffolding by forming specific isopeptide bonds between keratin intermediate filaments and keratin-associated proteins.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on jidonline.org →
    Discuss this study in the Community →

    Research cited in this study 23

    1. Hair: The Most Sophisticated Biological Composite Material Chemical Society Reviews · 2007
    2. Cystatin M/E Is a High Affinity Inhibitor of Cathepsin V and Cathepsin L by a Reactive Site Distinct from the Legumain-binding Site Journal of biological chemistry/˜The œJournal of biological chemistry · 2006
    3. Proteome Analysis of Human Hair Shaft Molecular & Cellular Proteomics · 2006
    4. Human Hair Keratin-Associated Proteins International review of cytology · 2006
    5. Human Hair Keratin-Associated Proteins ˜The œjournal of investigative dermatology. Symposium proceedings/˜The œJournal of investigative dermatology symposium proceedings · 2005
    6. Transglutaminase 5 Expression in Human Hair Follicle Journal of Investigative Dermatology · 2005
    7. Human KAP Genes: Only Half of It? Extensive Size Polymorphisms in Hair Keratin-Associated Protein Genes ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2005
    8. Hair Keratin Pattern in Human Hair Follicles Grown In Vitro Experimental dermatology · 2003
    9. Characterization of a First Domain of Human High Glycine-Tyrosine and High Sulfur Keratin-Associated Protein Genes on Chromosome 21q22.1 Journal of biological chemistry/˜The œJournal of biological chemistry · 2002
    10. Polymorphisms in the Human High Sulfur Hair Keratin-Associated Protein 1, KAP1, Gene Family Journal of biological chemistry/˜The œJournal of biological chemistry · 2002
    11. HKAP1.6 And HKAP1.7, Two Novel Human High Sulfur Keratin-Associated Proteins Are Expressed In The Hair Follicle Cortex ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2002
    12. The Catalog of Human Hair Keratins Journal of Biological Chemistry · 2001
    13. Characterization of a Cluster of Human High/Ultrahigh Sulfur Keratin-Associated Protein Genes Embedded in the Type I Keratin Gene Domain on Chromosome 17q12-21 Journal of biological chemistry/˜The œJournal of biological chemistry · 2001
    14. The Catalog of Human Hair Keratins Journal of biological chemistry/˜The œJournal of biological chemistry · 1999
    15. The Fate of Trichohyalin Journal of biological chemistry/˜The œJournal of biological chemistry · 1997
    16. Immunohistochemical Analysis of Tissue Remodeling During the Anagen-Catagen Transition of the Human Hair Follicle British Journal of Dermatology · 1997
    17. The Role of Keratin Proteins and Their Genes in the Growth, Structure, and Properties of Hair Birkhäuser Basel eBooks · 1997
    18. The Proximal Promoter of the Human Transglutaminase 3 Gene Journal of biological chemistry/˜The œJournal of biological chemistry · 1996
    19. The Deduced Sequence of the Novel Protransglutaminase E (TGase3) of Human and Mouse Journal of Biological Chemistry · 1993
    20. Regulation of Keratin Gene Expression in Hair Follicle Differentiation Annals of the New York Academy of Sciences · 1991
    21. Human Hair Growth In Vitro Journal of Cell Science · 1990
    22. The Complement of Native Alpha-Keratin Polypeptides of Hair-Forming Cells: A Subset of Eight Polypeptides That Differ from Epithelial Cytokeratins Differentiation · 1986
    23. Transglutaminase from Hair Follicle of Guinea Pig Proceedings of the National Academy of Sciences · 1972

    Related research 6

    1. Transglutaminase-3 Enzyme: A Putative Actor in Human Hair Shaft Scaffolding? ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2008
    2. Hair Keratinization in Health and Disease Dermatologic clinics · 1996
    3. Architecture of Reconstructed Epidermis on Collagen Lattices Varies According to the Method Used: A Comparative Study Skin Pharmacology and Physiology · 1990
    4. Expression of Keratin K14 in the Epidermis and Hair Follicle: Insights Into Complex Programs of Differentiation The Journal of Cell Biology · 1989
    5. Transglutaminase-Mediated Cross-Linking in Mammalian Epidermis 1984
    6. Biochemistry of Transglutaminases and Cross-Linking in the Skin Journal of Investigative Dermatology · 1983