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Did you mean Transglutaminase?

GlossaryTransglutaminase

enzyme that cross-links proteins, crucial for hair strength

Transglutaminase, often abbreviated as TGase, is an enzyme that catalyzes the formation of covalent bonds between proteins, specifically by linking the amino acid glutamine to lysine. This process is crucial for various biological functions, including blood clotting, skin formation, and hair follicle development. In the context of hair, transglutaminase helps strengthen the hair shaft by cross-linking keratin proteins, contributing to hair's structural integrity and resilience.

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research The Fate of Trichohyalin

135 citations , October 1997 in “Journal of biological chemistry/The Journal of biological chemistry”

Trichohyalin is modified by enzymes to form strong structures in hair cells.

research Cornification

September 2018

Cornification is the process where living skin cells die to create a protective barrier, and problems with it can cause skin diseases.

research Apoptosis in Human Skin Development: Morphogenesis, Periderm, and Stem Cells

253 citations , March 1994 in “Developmental dynamics”

Apoptosis is essential for human skin development and forming a functional epidermis.

research The Structure of Human Trichohyalin: Potential Multiple Roles as a Functional EF-Hand-Like Calcium-Binding Protein, a Cornified Cell Envelope Precursor, and an Intermediate Filament-Associated (Cross-Linking) Protein

161 citations , June 1993 in “Journal of Biological Chemistry”

Trichohyalin helps in hair and skin cell structure and function by binding calcium and linking proteins.

research Ultrastructural Visualization of Cross-Linked Protein Features in Epidermal Appendages

43 citations , July 1994 in “Journal of Cell Science”

Cross-linked proteins help maintain the structure of hair, feathers, and hagfish teeth.

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