Ribonucleic Acids Coding for the Keratin Complex of Hair

    January 1981
    G.E. Rogers, M. J. Frenkel, R.A.C. Lock
    TLDR Keratin proteins in hair are complex and come from multiple gene families.
    The document discussed the regulation of keratinization in hair follicles, focusing on the expression of genes coding for keratin proteins. It identified three major classes of keratin proteins based on molecular weight and chemical properties: low-sulfur, high-sulfur, and high-glycine-tyrosine groups. The study highlighted the complexity of these protein groups and the uncertainty regarding their genetic origins or posttranslational modifications. Despite the lack of detailed understanding of the structural framework of the keratin complex, it was clear that each class of keratin proteins was composed of multiple gene families.
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