Image

    Hair Growth Activity of Three Plants of the Polynesian Cosmetopoeia and Their Regulatory Effect on Dermal Papilla Cells

    September 2020 in “ Molecules ”
    Kristelle Hughes, Raimana Ho, Stéphane Greff … Phila Raharivelomanana
    Studysummary In this study, extracts from three Polynesian plants—Bidens pilosa, Calophyllum inophyllum, and Fagraea berteroana—were found to increase dermal papilla cell proliferation and modulate hair growth-related gene expression, suggesting potential for stimulating hair growth.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on mdpi.com →
    Discuss this study in the Community →

    Research cited in this study 42

    1. A Selection of Eleven Plants Used as Traditional Polynesian Cosmetics and Their Development Potential as Anti-Aging Ingredients, Hair Growth Promoters, and Whitening Products Journal of Ethnopharmacology · 2019
    2. Beta-Catenin-Mediated Hair Growth Induction Effect of 3,4,5-Tri-O-Caffeoylquinic Acid Aging · 2019
    3. Ginsenoside Rb1 Promotes the Growth of Mink Hair Follicle via PI3K/AKT/GSK-3β Signaling Pathway Life Sciences · 2019
    4. The Mesenchymal Niche of the Hair Follicle Induces Regeneration by Releasing Primed Progenitors from Inhibitory Effects of Quiescent Stem Cells Cell Reports · 2018
    5. Female Pattern Hair Loss: A Clinical, Pathophysiologic, and Therapeutic Review International Journal of Women's Dermatology · 2018
    6. Costunolide Promotes the Proliferation of Human Hair Follicle Dermal Papilla Cells and Induces Hair Growth in C57BL/6 Mice Journal of Cosmetic Dermatology · 2018
    7. Nature-Derived Lignan Compound VB-1 Exerts Hair Growth-Promoting Effects by Augmenting Wnt/β-Catenin Signaling in Human Dermal Papilla Cells PeerJ · 2018
    8. Androgen Modulation of Wnt/β-Catenin Signaling in Androgenetic Alopecia Archives of Dermatological Research · 2018
    9. Hair Regenerative Mechanisms of Red Ginseng Oil and Its Major Components in the Testosterone-Induced Delay of Anagen Entry in C57BL/6 Mice Molecules · 2017
    10. Undariopsis Peterseniana Promotes Hair Growth by the Activation of Wnt/β-Catenin and ERK Pathways Marine Drugs · 2017
    11. Effect of Sinapic Acid on Hair Growth Promotion in Human Hair Follicle Dermal Papilla Cells via Akt Activation Archives of Dermatological Research · 2017
    12. Hair Growth-Promoting Effect of Geranium Sibiricum Extract in Human Dermal Papilla Cells and C57BL/6 Mice BMC Complementary and Alternative Medicine · 2017
    13. Novel ALK5 Inhibitor TP0427736 Reduces TGF-β Induced Growth Inhibition in Human Outer Root Sheath Cells and Elongates Anagen Phase in Mouse Hair Follicles Pharmacological Reports · 2017
    14. Stress-Induced Premature Senescence of Dermal Papilla Cells Compromises Hair Follicle Epithelial-Mesenchymal Interaction Journal of Dermatological Science · 2017
    15. Attenuation of Dickkopf 1-Induced Hair Growth Inhibition in Cultured Human Hair Follicles by Tianeptine Annals of Dermatology · 2017
    16. 3-Deoxysappanchalcone Promotes Proliferation of Human Hair Follicle Dermal Papilla Cells and Hair Growth in C57BL/6 Mice by Modulating WNT/β-Catenin and STAT Signaling Biomolecules & Therapeutics · 2016
    17. Human Platelet Lysate Versus Minoxidil Stimulates Hair Growth by Activating Anagen Promoting Signaling Pathways Biomedicine & Pharmacotherapy · 2016
    18. An Investigation of Crosstalk Between Wnt/β-Catenin and Transforming Growth Factor-β Signaling in Androgenetic Alopecia Medicine · 2016
    19. Differential Expression Between Human Dermal Papilla Cells from Balding and Non-Balding Scalps Reveals New Candidate Genes for Androgenetic Alopecia Journal of Investigative Dermatology · 2016
    20. Effects of Flavonoid Derivatives on Human Microvascular Endothelial Cells Natural Product Research · 2016
    21. Protopanaxatriol Type Ginsenoside Re Promotes Cyclic Growth of Hair Follicles via Inhibiting Transforming Growth Factor β Signaling Cascades Biochemical and Biophysical Research Communications · 2016
    22. Wnt5a Suppresses β-Catenin Signaling During Hair Follicle Regeneration International Journal of Medical Sciences · 2016
    23. A Guide to Studying Human Hair Follicle Cycling In Vivo Journal of Investigative Dermatology · 2015
    24. The Dermal Papilla: An Instructive Niche for Epithelial Stem and Progenitor Cells in Development and Regeneration of the Hair Follicle Cold Spring Harbor Perspectives in Medicine · 2014
    25. Hair Follicle Signaling Networks: A Dermal Papilla–Centric Approach Journal of Investigative Dermatology · 2013
    26. The Promoting Effect of Ishige Sinicola on Hair Growth Marine Drugs · 2013
    27. Dermal Papilla Cell Number Specifies Hair Size, Shape, and Cycling, and Its Reduction Causes Follicular Decline Development · 2013
    28. Visible-To-Near IR Quantum Dot-Based Hypermulticolor High-Content Screening of Herbal Medicines for Efficacy Monitoring of Hair Growth Promotion and Hair Loss Inhibition SLAS discovery · 2012
    29. Androgen Actions on the Human Hair Follicle: Perspectives Experimental Dermatology · 2012
    30. Mesenchymal–Epithelial Interactions During Hair Follicle Morphogenesis and Cycling Seminars in Cell & Developmental Biology · 2012
    31. New Activators and Inhibitors in the Hair Cycle Clock: Targeting Stem Cells’ State of Competence Journal of Investigative Dermatology · 2012
    32. Minoxidil Activates β-Catenin Pathway in Human Dermal Papilla Cells: A Possible Explanation for Its Anagen Prolongation Effect Journal of Dermatological Science · 2011
    33. Molecular Basis of Androgenetic Alopecia: From Androgen to Paracrine Mediators Through Dermal Papilla Journal of Dermatological Science · 2010
    34. Biphasic Effects of Minoxidil on the Proliferation and Differentiation of Normal Human Keratinocytes Skin Pharmacology and Physiology · 2009
    35. Keratinocyte Growth Inhibition Through the Modification of Wnt Signaling by Androgen in Balding Dermal Papilla Cells ˜The œJournal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism · 2009
    36. Molecular Dissection of Mesenchymal–Epithelial Interactions in the Hair Follicle PLoS biology · 2005
    37. Molecular Principles of Hair Follicle Induction and Morphogenesis BioEssays · 2005
    38. Effect of Minoxidil on Proliferation and Apoptosis in Dermal Papilla Cells of Human Hair Follicle Journal of Dermatological Science · 2004
    39. Topical Application of a Protein Kinase C Inhibitor Reduces Skin and Hair Pigmentation ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2004
    40. A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men Journal of The American Academy of Dermatology · 2002
    41. Procyanidin B-2 Extracted from Apples Promotes Hair Growth: A Laboratory Study British journal of dermatology/British journal of dermatology, Supplement · 2002
    42. Cyclosporin A Promotes Hair Epithelial Cell Proliferation and Modulates Protein Kinase C Expression and Translocation in Hair Epithelial Cells Journal of Investigative Dermatology · 2001

    Related research 6

    1. Activation of Beta-Catenin Signaling in CD133-Positive Dermal Papilla Cells Drives Postnatal Hair Growth PLOS ONE · 2016
    2. Dermal Papilla-Derived Wnt Ligands Are Required for Adult Hair Follicle Growth Journal of Investigative Dermatology · 2016
    3. Dermal Sheath Cells Contribute to Postnatal Hair Follicle Growth and Cycling Journal of Dermatological Science · 2016
    4. Blockade of S100A3 Activity Inhibits Murine Hair Growth Genetics and Molecular Research · 2015
    5. Hair Follicle Expression of 1,25-Dihydroxyvitamin D3 Receptors During the Murine Hair Cycle British Journal of Dermatology · 2006
    6. An Estrogen Receptor Pathway Regulates the Telogen-Anagen Hair Follicle Transition and Influences Epidermal Cell Proliferation Proceedings of the National Academy of Sciences of the United States of America · 1996