TLDR Eleven traditional Polynesian plants show potential for natural anti-aging, hair growth, and skin brightening products.
In 2019, researchers investigated the potential of 11 traditional Polynesian plants for use in anti-aging, anti-blemish, and hair care products. The plants were selected based on their traditional use in Polynesian cosmetics, their biogeographical status, their phytochemistry of cosmetic interest, and their availability and absence from the UICN list. The study found that these plants showed promise for development as natural anti-aging or hair care products and as skin brightening agents. One plant, Calophyllum inophyllum, was noted for its diverse applications, including its use in India for treating baldness and promoting hair growth. The seed oil of C. inophyllum was also used for treating various skin diseases and joint pains. In Polynesia, parts of C. inophyllum were used as anti-aging agents, and a 2017 study found that the fruit induced apoptosis in breast cancer MCF-7 cell line via the mitochondrial pathway in a dose-dependent manner.
56 citations,
January 2019 in “Lancet” JAK inhibitors help regrow hair in alopecia areata patients, improving their quality of life.
25 citations,
March 2017 in “Archives of Dermatological Research” Sinapic acid may help hair growth by activating a specific cell pathway.
47 citations,
August 2016 in “Fitoterapia” Some herbs and their components might help treat hair loss by affecting various biological pathways, but more research and regulation are needed.
18 citations,
July 2016 in “Medicine” Wnt/β-catenin and TGF-β pathways affect hair loss, and activating Wnt/β-catenin could be a potential treatment.
212 citations,
September 2015 in “Journal of Investigative Dermatology” The document provides a method to classify human hair growth stages using a model with human scalp on mice, aiming to standardize hair research.
136 citations,
July 2014 in “Proceedings of the National Academy of Sciences of the United States of America” FGF5 gene mutations cause unusually long eyelashes by affecting hair growth regulation.
300 citations,
August 2012 in “Seminars in Cell & Developmental Biology” The conclusion is that certain cell interactions and signals are crucial for hair growth and regeneration.
68 citations,
April 2012 in “Journal of Investigative Dermatology” The conclusion is that Fgf18 and Tgf-ß signaling could be targeted for hair loss treatments.
122 citations,
November 2010 in “Journal of Dermatological Science” Male pattern baldness involves hormones and cell signals affecting hair growth.
5 citations,
September 2020 in “Molecules” Extracts from three Polynesian plants were found to promote hair growth by affecting cell growth and gene expression related to hair.
1 citations,
February 2024 in “Diversity” African plants can treat hair issues and may help with diabetes.
Natural products may help treat hair loss by promoting hair growth with fewer side effects.
1 citations,
January 2017 in “Social Science Research Network” The document suggests creating a secure database for indigenous knowledge and recommends that the TKDL actively fight patents that slightly alter traditional knowledge.
1 citations,
June 2016 in “Yāftah/hā-yi nuvīn dar ̒ulūm-i zīstī” Sheep testis extract significantly improves wound healing and hair growth in rats.