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Research

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research Co-delivering Retinol and Niacinamide via Liposomes: Enhanced Stability, Efficient Skin Permeation, and Improved Anti-Aging/Skin-Brightening Efficacy

August 2025

This study found that the RN-Lip co-delivery system enhanced the stability and skin permeation of retinol and niacinamide, leading to improved anti-aging and skin-brightening effects in vitro.

research 560 The molecular mechanism of PCE-DP, a novel brightening active ingredient

September 2019 in “Journal of Investigative Dermatology”

This study observed that PCE-DP may improve skin pigmentation by increasing epidermal turnover and inhibiting melanin uptake and inflammation in human epidermal keratinocytes.

A Selection of Eleven Plants Used as Traditional Polynesian Cosmetics and Their Development Potential as Anti-Aging Ingredients, Hair Growth Promoters, and Whitening Products

research A selection of eleven plants used as traditional Polynesian cosmetics and their development potential as anti-aging ingredients, hair growth promoters and whitening products

13 citations , August 2019 in “Journal of Ethnopharmacology”

This study assessed 11 plants from French Polynesia for their potential development as sustainable natural cosmetics, particularly anti-aging and hair care products, based on their traditional uses and preliminary screening results.

research Formulation and Evaluation of Herbal Face Pack

1 citations , April 2025 in “International Journal for Research in Applied Science and Engineering Technology”

In this study, researchers developed an herbal face pack using ingredients like turmeric and neem, assessing its safety and efficacy. They reported that the formulation's properties, such as pH and stability, support its potential as a safe and effective alternative to synthetic skincare products.

The Genus Astragalus Species as an Emerging Source of Bioactive Phytochemicals: A Review of Dermatological and Cosmetic Applications

research The Genus Astragalus Species as an Emerging Source of Bioactive Phytochemicals: A Review of Dermatological and Cosmetic Applications

April 2026 in “Cosmetics”

In this review, several studies on Astragalus species, particularly Astragalus membranaceus, highlight their skin rejuvenating, photoprotective, antimicrobial, and wound-healing properties, though the authors note limitations due to reliance on non-human studies and short trial durations.

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Community Join

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community Minoxidil has been both a blessing and a curse

153 upvotes 2 months ago

Minoxidil can cause dark circles and aging appearance in some users, leading them to stop its use despite hair regrowth benefits. Some users suggest reducing dosage or switching to oral minoxidil to minimize side effects.

community 8 Month Result - What a good HT, Dutasteride, and Minoxidil does to your hair.

in Update 92 upvotes 2 years ago

OP shared an 8-month update on hair transplant results, using Dutasteride, oral Minoxidil, and Biotin. OP also discussed a simple skincare routine with Cerave products and sunscreen.

community Minoxidil Eye Bags and Dark Circles

24 upvotes 3 years ago

Minoxidil users report dark circles and eye bags. Solutions include water pills, caffeine serum, retinol, and collagen peptides.

community (MTF 35) Results of 18 Months of HRT

775 upvotes 8 months ago

A transgender woman experienced significant hair regrowth after 18 months of hormone replacement therapy (HRT) with estrogen and bicalutamide. The discussion notes HRT's effectiveness for hair regrowth but warns against its use for cisgender men due to feminizing effects.

community 6 months on dutast and minoxodil, hair growing like weeds now!

in Progress Pictures 618 upvotes 1 year ago

A woman experienced significant hair regrowth after six months of using dutasteride and minoxidil, despite initial hair loss due to androgenetic alopecia. She reported minimal side effects and highlighted the effectiveness of these treatments for women, despite doctors' hesitancy to prescribe them.

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Learn

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learn Melatonin

Can melatonin cause side effects on the skin or hair? Melatonin may cause hair loss or thinning in some users, but evidence is limited.

learn Scalp Micropigmentation

Does scalp micropigmentation work on all skin tones and hair colors? Scalp micropigmentation can be customized for various skin tones and hair colors.
Is scalp micropigmentation suitable for people with sensitive skin? Providers say scalp micropigmentation suits most skin types and describe patch tests, hypoallergenic pigments and a skin consultation for sensitive skin. These are provider claims rather than independent safety evidence, and pigment reactions remain a risk.

learn retinol

How does retinol improve scalp health and prepare the skin for other hair growth treatments? Retinol improves scalp health by promoting cellular turnover and reducing congestion.

learn Hyaluronic Acid

Does hyaluronic acid really hydrate the scalp, or is it mainly for skin care? Hyaluronic acid can hydrate the scalp, but its effectiveness may vary.

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Clinics

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Experts

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35
SMP Specialist
Noelle Skin
Nice, France

Noelle Skin