Hair Growth-Promoting Effect of Geranium Sibiricum Extract in Human Dermal Papilla Cells and C57BL/6 Mice

    William A. Boisvert, Miri Yu, Young-Bin Choi … Sang-Hyun Lee
    Studysummary In this study, Geranium sibiricum L. extract promoted hair growth in vitro with human dermal papilla cells and in vivo in mice, outperforming minoxidil by proliferating cells and stimulating growth factor expression, suggesting its potential as a hair growth treatment.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on bmccomplementmedtherapies.biomedcentral.com →
    Discuss this study in the Community →

    Research cited in this study 15

    1. Neuroendocrinology of the Hair Follicle: Principles and Clinical Perspectives Trends in Molecular Medicine · 2014
    2. Effects of Glucocorticoid on Human Dermal Papilla Cells In Vitro The Journal of Steroid Biochemistry and Molecular Biology · 2012
    3. Androgen Actions on the Human Hair Follicle: Perspectives Experimental Dermatology · 2012
    4. Hair Growth Promoting Effect of Zizyphus Jujuba Essential Oil Food and Chemical Toxicology · 2010
    5. Biphasic Effects of Minoxidil on the Proliferation and Differentiation of Normal Human Keratinocytes Skin Pharmacology and Physiology · 2009
    6. The Hair Cycle Journal of Cell Science · 2006
    7. Biological Characterization of Cultured Dermal Papilla Cells and Hair Follicle Regeneration In Vitro and In Vivo Chinese Medical Journal · 2006
    8. An Open, Randomized, Comparative Study of Oral Finasteride and 5% Topical Minoxidil in Male Androgenetic Alopecia Dermatology · 2004
    9. Molecular Control of Epithelial-Mesenchymal Interactions During Hair Follicle Cycling ˜The œjournal of investigative dermatology. Symposium proceedings/˜The œJournal of investigative dermatology symposium proceedings · 2003
    10. Onion Juice (Allium Cepa L.), A New Topical Treatment For Alopecia Areata The Journal of Dermatology · 2002
    11. Hair Growth Effect of Minoxidil Folia Pharmacologica Japonica · 2002
    12. Photographic Documentation of the Effectiveness of 1 mg Oral Finasteride in the Treatment of Androgenic Alopecia in Men in Routine General Practice in Switzerland PubMed · 2001
    13. Finasteride Drugs · 1999
    14. Lipid Peroxides Induce Early Onset of Catagen Phase in Murine Hair Cycles International Journal of Molecular Medicine · 1998
    15. Effects of Epidermal Growth Factor on the Morphology and Patterns of DNA Synthesis in Isolated Human Hair Follicles ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1994

    Related research 7

    1. The Potential Role of Fibroblast-Derived Multi-Peptide Factors in Activation of Growth Factors and Beta-Catenin in Hair Follicle Cells Journal of Cosmetic Dermatology · 2022
    2. Hair Growth-Promoting Effects of Camellia Seed Cake Extract in Human Dermal Papilla Cells and C57BL/6 Mice Journal of Cosmetic Dermatology · 2022
    3. Hair Growth-Promoting Effect of Geranium Sibiricum Extract in Human Dermal Papilla Cells and C57BL/6 Mice BMC Complementary and Alternative Medicine · 2017
    4. Hair-Growth-Promoting Effect of Conditioned Medium of High Integrin α6 and Low CD71 Positive Keratinocyte Cells International Journal of Molecular Sciences · 2015
    5. Correlation Between Hair Physiology and Hair Loss 2005
    6. Promoted Growth of Murine Hair Follicles by Controlled Release of Growth Factors from Biodegradable Hydrogel Key Engineering Materials · 2005
    7. The Chemotactic Effect of a Dermal Papilla Cell-Derived Factor on Outer Root Sheath Cells Journal of Dermatological Science · 2001