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GlossaryDermal Papilla Cells (HDPCs)

specialized cells at hair follicle base crucial for hair growth

Dermal Papilla Cells (DPCs) are specialized cells located at the base of hair follicles. They play a crucial role in hair growth and regeneration by interacting with surrounding cells to regulate the hair growth cycle. These cells are essential for the formation of new hair follicles and are a key focus in research on hair loss treatments and regenerative medicine.

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Wnt/β-Catenin and ERK Pathway Activation: A Possible Mechanism of Photobiomodulation Therapy with Light-Emitting Diodes That Regulate the Proliferation of Human Outer Root Sheath Cells

research Wnt/β-Catenin and ERK Pathway Activation: A Possible Mechanism of Photobiomodulation Therapy with Light-Emitting Diodes That Regulate the Proliferation of Human Outer Root Sheath Cells

43 citations, September 2017 in “Lasers in Surgery and Medicine”

LED light therapy may help hair growth by activating certain cell pathways.

research Cepharanthine Induces Proliferation of Human Dermal Papilla Cells and Stimulates Vascular Endothelial Growth Factor Expression Through Increased Intracellular Calcium Mobilization and Hypoxia-Inducible Factor Activation

7 citations, December 2020 in “Clinical and Experimental Dermatology”

Cepharanthine may help hair growth by boosting cell growth and VEGF expression.

research Overexpression of miR-122 Promotes Apoptosis of Dermal Papilla Cells by Directly Targeting IGF1R in Androgenetic Alopecia

2 citations, November 2021 in “Cell Biology International”

miR-122 causes hair loss by killing hair cells.

research The Hair Growth-Promoting Effect of Gardenia Florida Fruit Extract and Its Molecular Regulation

1 citations, September 2022 in “Evidence-based Complementary and Alternative Medicine”

Gardenia florida fruit extract may help hair grow and needs more research to understand how.

research The Effect of JAK Inhibitor on Survival, Anagen Re-Entry, and Hair Follicle Immune Privilege Restoration in Human Dermal Papilla Cells

16 citations, July 2020 in “International Journal of Molecular Sciences”

Ruxolitinib may help treat hair loss by reducing inflammation, promoting hair growth signals, and protecting hair follicle immunity.

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community NMN Promotes Cell Proliferation and Hair Growth by Reducing Oxidative Stress

in Research/Science 14 upvotes 8 months ago

NMN shows promise in promoting hair growth by reducing oxidative stress and weakening androgens. It may be a beneficial addition to hair loss treatments like Minoxidil and Finasteride.

community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 41 upvotes 5 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community redensyl - follicle stem cell activator any experiences?

in Question 9 upvotes 7 years ago

A Swiss product called Redensyl, which is supposed to target hair follicle stem cells and has recently been marketed in Europe. The post inquires if anyone has had any experience with the product.

community Red Ginseng Extract Promotes the Hair Growth in Cultured Human Hair Follicles

17 upvotes 6 years ago

The conversation is about hair loss treatments, specifically discussing the effectiveness of Red Ginseng Extract in promoting hair growth. Other treatments mentioned include Minoxidil, finasteride, and RU58841.