TLDR Using hydrogels to slowly release growth factors can effectively boost hair growth in mice.
The study from 2005 examined the impact of growth factors bFGF, HGF, and VEGF, delivered through biodegradable hydrogels, on hair follicle growth in 29-day-old male C3H mice. The hydrogels containing growth factors were implanted subcutaneously and led to significant increases in skin darkness, blood vessel formation, hair follicle tissue area, and hair shaft length compared to controls. Neither empty hydrogels nor direct injections of growth factors had similar effects. The research concluded that controlled release of growth factors from hydrogels effectively promoted the hair growth cycle in mice.
520 citations,
February 2001 in “Journal of Clinical Investigation” VEGF helps hair grow and determines follicle size by increasing blood vessel growth.
90 citations,
October 1996 in “Dermatologic Clinics” Growth factors are crucial for hair development and could help treat hair diseases.
58 citations,
January 1987 in “Archives of Dermatological Research” EGF and FGF boost hair cell growth, hydrocortisone slows it, and minoxidil doesn't affect it.
76 citations,
February 2021 in “International Journal of Molecular Sciences” Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.
2 citations,
September 2022 in “Cytotherapy” Fat-derived stem cells show promise for treating skin issues and improving wound healing, but more research is needed to confirm the best way to use them.
19 citations,
January 2017 in “Stem Cells International” Adipose-derived stem cells show promise in treating skin conditions like vitiligo, alopecia, and nonhealing wounds.
24 citations,
August 2021 in “Biologics” Stem cell therapy shows promise in improving burn wound healing.
January 2012 in “Elsevier eBooks” New treatments for skin and hair repair show promise, but further improvements are needed.
