research Alopecia Areata: A tissue specific autoimmune disease of the hair follicle
This review discusses alopecia areata as a model for studying tissue-directed autoimmune diseases and reports no new clinical findings.
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5 / 1000+ resultsresearch 083 More Expression of IL-17 than IFN-γ from CD49a-negative Tissue-Resident Memory T (Trm) cells at the Hair Bulge and Hair Bulb Region in the Scalp of Chronic Alopecia Areata Patients according to the Foxp3+mTregs depletion
This study found that in chronic alopecia areata, increased IL-17 expression and CD8+CD49a-Trm cell infiltration in hair follicles were associated with more severe histopathologic gradings, while Foxp3+mTreg infiltration decreased.
research Cartilage oligomeric matrix protein (COMP) forms part of the connective tissue of normal human hair follicles
This study identifies cartilage oligomeric matrix protein (COMP) as a key extracellular matrix component in human hair follicle cycling, potentially regulated by TGFβ signaling, and suggests its importance in normal hair follicle biology.
research Hair follicles as immune targets: unraveling cellular players, cytokine crosstalk, and precision pathways for future therapy of alopecia areata
This review highlights that alopecia areata is characterized by three immune endotypes, and while JAK inhibitors offer temporary control, upcoming multi-omics diagnostics and immune reprogramming strategies may achieve longer-lasting remission, according to this analysis.
research Hair-follicle associated pluripotent (HAP) stem cells differentiate to beating cardiac tissue sheets
Hair follicle stem cells can become heart muscle cells.
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5 / 1000+ resultscommunity Why not move miniaturized hair follicles somewhere else to treat them? Alternative to hair cloning?
Exploring the idea of transplanting miniaturized hair follicles to healthier areas to potentially reverse hair loss, with concerns about DHT sensitivity and scar tissue formation. The conversation also humorously considers using mice for hair growth experiments.
community Can pp405 revive dead follicles for long time bald people? Are those even dead? After 10+ years bald
PP405 may revive dormant hair follicles but is unlikely to help with long-term baldness where follicles are replaced by scar tissue. It is seen as a potential adjunct to treatments like minoxidil and finasteride, but its effectiveness on deeply fibrotic or scarred areas is doubtful.
community DUPA, Non Responders and Connective Tissue Disorders
A 27-year-old male with diffuse hair loss, including the donor area, did not respond to finasteride, dutasteride, or minoxidil. He suspects his hair loss may be linked to a mild connective tissue disorder, possibly affecting the structural support of hair follicles, rather than being purely hormonal.
community What Are the Technicalities of Curved Hair Transplantation?
Curved hair transplantation requires specialized tools and techniques to avoid damaging hair follicles, with modified FUE being the preferred method. Proper extraction and implantation angles are crucial to prevent complications like keloids and sterile folliculitis.
community Topical Metformin for Hair Transplant donor area skin/hair regeneration?
Topical Metformin shows potential for regenerating hair follicles and minimizing scarring in hair transplant donor areas, similar to Verteporfin but without its side effects. The discussion suggests considering Metformin for post-hair transplant care, though more human trials are needed.
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10 / 800 results- What role does Osteopontin play in protecting and repairing hair follicles? In mouse studies osteopontin switched on hair stem cells, but an osteopontin-derived peptide suppressed growth in human scalp tissue. Whether it protects human follicles is unknown.
- Does niacinamide support hair follicle nutrition? Niacinamide is a precursor of NAD+, a molecule cells use for energy. Whether it affects hair follicles in people has not been tested.
- Will scalp micropigmentation damage my existing hair or follicles? Providers say SMP sits above the hair follicles and does not harm them. No study has tested this, and infection or scarring from any tattoo can affect the skin.
- Can sulforaphane protect hair follicles from inflammation and damage? In lab and mouse studies, sulforaphane reduced markers of inflammation and oxidative stress. No human study has tested whether it protects hair follicles.
- Can daily Fluridil application stop hair follicle miniaturization? The single published fluridil trial (43 men; placebo-controlled for 3 months, then all on fluridil to 9 months) reported more hairs in the growth phase, but it never measured follicle diameter and has not been replicated — so whether daily use stops miniaturization is unproven, and community users describe stabilization rather than regrowth.
learn Thymosin Beta 4
learn Platelet-Rich Plasma
Concentrate of your own blood platelets, injected into the scalp
learn Osteopontin
learn GHK-Cu
Copper peptide used in skin and hair cosmetics
learn Lavender
Plant essential oil used in scalp products
learn Niacinamide
learn Scalp Micropigmentation
learn Sulforaphane
learn Fluridil
learn Hair Transplant
Surgery that moves hair follicles from the back of the scalp to thinning areas
Clinics
6 / 13 results
Hair Loss TreatmentsLabwest Hair Tissue AnalysisPerth, WA · AU- Hair Loss TreatmentsHair Follicle ImagingJaffa · IL
Hair TransplantHair Loss TreatmentsSMPNeo Follicle Hair TransplantBengaluru, Karnataka · IN
Hair TransplantHair Loss TreatmentsFollicle Hair ClinicLondon, England · GB- Hair TransplantMicro Follicle Hair TransplantKanayannur, Kerala · IN
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Hair TransplantFollicle - Premium Hair TransplantsSydney, NSW · AU