Effects of Flavonoid Derivatives on Human Microvascular Endothelial Cells

    March 2016 in “ Natural Product Research ”
    Eleonora Bassino, Susanna Antoniotti, F Gasparri, Luca Munaron
    Studysummary This study found that baicalin promotes human microvascular endothelial cell proliferation, while visnadin and minoxidil enhance tubulogenesis, with hesperidin uniquely increasing VEGFR-2 phosphorylation compared to other compounds tested.
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    Research cited in this study 5

    1. The Inhibitory Effect of Scutellaria Baicalensis Extract and Its Active Compound, Baicalin, on the Translocation of the Androgen Receptor with Implications for Preventing Androgenetic Alopecia Planta Medica · 2014
    2. A Randomized, Active- and Placebo-Controlled Study of the Efficacy and Safety of Different Doses of Dutasteride Versus Placebo and Finasteride in the Treatment of Male Subjects with Androgenetic Alopecia Journal of The American Academy of Dermatology · 2014
    3. Hair Growth and Rejuvenation: An Overview Journal of Dermatological Treatment · 2010
    4. Control of Hair Growth and Follicle Size by VEGF-Mediated Angiogenesis Journal of Clinical Investigation · 2001
    5. Minoxidil Upregulates the Expression of Vascular Endothelial Growth Factor in Human Hair Dermal Papilla Cells British Journal of Dermatology · 1998