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GlossaryHenoch-Schönlein purpura (HSP)

condition causing small blood vessel inflammation and purplish skin rash

Henoch-Schönlein purpura (HSP), also known as IgA vasculitis, is a condition that causes inflammation and bleeding in the small blood vessels, primarily affecting the skin, joints, intestines, and kidneys. It is characterized by a distinctive purplish rash, often on the lower legs and buttocks, abdominal pain, and joint inflammation. The exact cause is unknown, but it often follows an upper respiratory infection and involves the deposition of IgA immune complexes in the affected tissues.

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research Association of HSPA1B SNP rs6457452 With Alopecia Areata in the Korean Population

12 citations , December 2013 in “Immunological Investigations”

The SNP rs6457452 is linked to a higher risk of alopecia areata in Koreans.

research TGF-β and HSP70 Profiles During Transformation of Yak Hair Follicles from Anagen to Catagen Stage

10 citations , February 2019 in “Journal of cellular physiology”

TGF-β2 helps yak hair follicles enter the regression phase, while HSP70 tries to prevent it.

Molecular Functional Analyses Revealed Essential Roles of HSP90 and Lamin A/C in Growth, Migration, and Self-Aggregation of Dermal Papilla Cells

research Molecular Functional Analyses Revealed Essential Roles of HSP90 and Lamin A/C in Growth, Migration, and Self-Aggregation of Dermal Papilla Cells

10 citations , May 2018 in “Cell death discovery”

HSP90 and lamin A/C are crucial for hair growth and could be targets for treating hair loss.

research HSP90 Inhibition and Cellular Stress Elicits Phenotypic Plasticity in Hematopoietic Differentiation

5 citations , October 2017 in “Cellular Reprogramming”

Inhibiting HSP90 increases cell adaptability and survival under stress.

research Regulation of Stem Cell Fate by HSPGs: Implication in Hair Follicle Cycling

3 citations , December 2022 in “npj Regenerative Medicine”

HSPGs help control stem cell behavior, affecting hair growth and offering a target for hair loss treatments.

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community (Topical) Quercetin might be a good add on to the hair loss stack

in Chat 8 upvotes 2 years ago

Quercetin might help with hair loss by inhibiting HSP-70, which increases androgen receptors. Concerns include its staining properties and unclear topical absorption.

community Aronia Chokeberry and Cyanidin 3-O-arabinoside for Hair Growth (AGA) Study

in Research/Science 14 upvotes 1 year ago

A natural compound called C3A from Aronia Chokeberry can help prevent hair loss by counteracting the effects of DHT. The user has been taking 50 grams of dried organic Aronia Chokeberry daily for 30 days and will update with photos in 60 days.