27 citations
,
January 2020 in “Experimental Dermatology”
This review discusses the role of immune cells in mammalian haircycle control and highlights their potential relevance to human hair cycling disorders, reporting no new clinical findings.
13 citations
,
January 2021 in “Histochemistry and Cell Biology”
In this study, human hair follicles showed varying expression of cholesterol transport proteins during the haircycle, suggesting a potential role of cholesterol in hair growth and cycling.
April 2021 in “The journal of investigative dermatology/Journal of investigative dermatology”
This study found that MPZL3 plays a crucial role in regulating the haircycle clock in mice, with its absence leading to accelerated hair follicle cycling and suggesting potential therapeutic pathways for alopecia treatment.
This study found that melatonin implants in cashmere goats significantly altered the expression pattern and co-expression of miRNAs, suggesting a possible role in inducing a second growth of cashmere.
38 citations
,
October 1988 in “Clinics in Dermatology”
This article reviews the historical development of understanding the hair growth cycle, particularly anagen, catagen, and telogen phases, and reports no new clinical findings.
Scalp hydration may influence hair growth by affecting the signaling pathways that control the hair growth cycle. Users suggest using facial moisturizer, aloe vera, and oils for scalp hydration.
Ashwagandha may help with hair loss by regulating thyroid function and reducing stress, but its effectiveness compared to finasteride or minoxidil is debated. Some users report positive effects on hair health, while others are skeptical of its benefits.
Breezula shows promising hair growth results, with up to 539% increase in hair count compared to placebo, and regulatory submissions are planned in the US and EU. Users are cautiously optimistic, noting the potential for Breezula to replace finasteride by targeting DHT without systemic effects.
A 24-year-old shares a 1-month update on his hair regrowth journey using 1mg oral finasteride, 10mg oral minoxidil, dermarolling, and pyrilutamide. Replies suggest it may take a few haircycles for vellus hairs to mature into normal hairs, with progress varying by individual.
Switching milk brands cleared scalp inflammation and other symptoms, but hair shedding continues. The user hopes shedding will stop as haircycles progress.
mTOR regulator and immunosuppressant used more recently for anti-aging and hair regrowth
Is rapamycin safe for long-term use on the scalp, or should it be used in cycles?There is no published human trial of topical rapamycin on the scalp, so nobody knows whether long-term use is safe; the idea of cycling it comes from community practice and theory, not from any study or guideline, and rapamycin for hair loss is an off-label use of a prescription immunosuppressant.
How long does it take for cyproterone to work on hair loss?There is no reliable published figure for how fast cyproterone works on hair loss: the hair cycle means nothing shows for months, the one randomised trial assessed women at twelve months, and community reports range from about six months to two years — with some people seeing no change at all.