A Study on Effects of Water-Soluble Minoxidil on Hair Growth in C57BL/6 Mice

January 2007 in “ Strait Pharmaceutical Journal ”

Yang Ya

water-soluble minoxidil anagen phase catagen phase hair cycle dermis thickness follicle number WMD

TLDR Water-soluble minoxidil effectively promoted hair growth in mice.

The study investigated the effects of water-soluble minoxidil (WMD) on hair growth in C57BL/6 mice. Mice were treated with 1%, 1.5%, and 3% WMD for 21 days. Results showed that WMD induced and prolonged the anagen phase and delayed the catagen phase of the hair cycle. The treatment led to earlier changes in skin color and significant improvements in hair length, dermis thickness, and follicle number, particularly in the 1.5% WMD group, compared to control mice. This indicated that WMD effectively promoted hair growth in the experimental mice.

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