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    Hair-Growth Potential of Ginseng and Its Major Metabolites: A Review on Its Molecular Mechanisms

    September 2018 in “ International Journal of Molecular Sciences ”
    Bu Young Choi
    Studysummary This review highlights the potential of ginseng and its metabolites in preventing hair loss, detailing their hair growth-promoting effects observed in numerous preclinical studies, and emphasizing the underlying mechanisms involved.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 36

    1. Role of Janus Kinase Inhibitors in the Treatment of Alopecia Areata Drug design, development and therapy · 2018
    2. Hair Regenerative Mechanisms of Red Ginseng Oil and Its Major Components in the Testosterone-Induced Delay of Anagen Entry in C57BL/6 Mice Molecules · 2017
    3. Panax Ginseng Extract Antagonizes the Effect of DKK-1-Induced Catagen-Like Changes of Hair Follicles International Journal of Molecular Medicine · 2017
    4. Inhibitory Effects of Polyacetylene Compounds from Panax Ginseng on Neurotrophin Receptor-Mediated Hair Growth Biological & Pharmaceutical Bulletin · 2017
    5. Negative Impact of Testosterone Deficiency and 5α-Reductase Inhibitors Therapy on Metabolic and Sexual Function in Men Advances in Experimental Medicine and Biology · 2017
    6. Protopanaxatriol Type Ginsenoside Re Promotes Cyclic Growth of Hair Follicles via Inhibiting Transforming Growth Factor β Signaling Cascades Biochemical and Biophysical Research Communications · 2016
    7. Collagenase IV Plays an Important Role in Regulating Hair Cycle by Inducing VEGF, IGF-1, and TGF-Beta Expression Drug Design Development and Therapy · 2015
    8. Protective Effect of Korean Red Ginseng Against Chemotherapeutic Drug-Induced Premature Catagen Development Assessed With Human Hair Follicle Organ Culture Model Journal of Ginseng Research · 2015
    9. The Androgen Receptor Antagonizes Wnt/β-Catenin Signaling in Epidermal Stem Cells Journal of Investigative Dermatology · 2015
    10. Collagenase IV Plays an Important Role in Regulating Hair Cycle by Inducing VEGF, IGF-1, and TGF-β Expression. PubMed · 2015
    11. Red Ginseng Extract Promotes Hair Growth in Cultured Human Hair Follicles Journal of Medicinal Food · 2014
    12. Alopecia Areata Is Driven by Cytotoxic T Lymphocytes and Is Reversed by JAK Inhibition Nature medicine · 2014
    13. Identification of Ultraviolet B Radiation-Induced MicroRNAs in Normal Human Dermal Papilla Cells Molecular Medicine Reports · 2014
    14. The Inductive Effect of Ginsenoside F2 on Hair Growth by Altering the WNT Signal Pathway in Telogen Mouse Skin European Journal of Pharmacology · 2014
    15. The Efficacy of 3% Minoxidil vs. Combined 3% Minoxidil and Korean Red Ginseng in Treating Female Pattern Alopecia International Journal of Dermatology · 2014
    16. Comparative Hair Restorer Efficacy of Medicinal Herb on Nude (Foxn1nu) Mice BioMed Research International · 2014
    17. Ginsenoside Rg3 Up-Regulates the Expression of Vascular Endothelial Growth Factor in Human Dermal Papilla Cells and Mouse Hair Follicles PTR. Phytotherapy research/Phytotherapy research · 2013
    18. Organic Causes of Erectile Dysfunction in Men Under 40 Urologia Internationalis · 2013
    19. Efficacy of Korean Red Ginseng in the Treatment of Alopecia Areata Journal of Ginseng Research · 2012
    20. Ginsenosides Rb1 and Rd Regulate Proliferation of Mature Keratinocytes Through Induction of p63 Expression in Hair Follicles PTR. Phytotherapy research/Phytotherapy research · 2012
    21. Androgen Actions on the Human Hair Follicle: Perspectives Experimental Dermatology · 2012
    22. VEGF Induces Proliferation of Human Hair Follicle Dermal Papilla Cells Through VEGFR-2-Mediated Activation of ERK Experimental Cell Research · 2012
    23. Fructus Panax Ginseng Extract Promotes Hair Regeneration in C57BL/6 Mice Journal of Ethnopharmacology · 2011
    24. Phytochemical Investigation and Hair Growth Studies on the Rhizomes of Nardostachys Jatamansi DC Pharmacognosy magazine · 2011
    25. Genome-Wide Association Study in Alopecia Areata Implicates Both Innate and Adaptive Immunity Nature · 2010
    26. Study of the Efficacy of Korean Red Ginseng in the Treatment of Androgenic Alopecia Journal of Ginseng Research · 2009
    27. Maintenance of Hair Follicle Immune Privilege Is Linked to Prevention of NK Cell Attack Journal of Investigative Dermatology · 2007
    28. Control of Human Hair Growth by Neurotrophins: Brain-Derived Neurotrophic Factor Inhibits Hair Shaft Elongation, Induces Catagen, and Stimulates Follicular Transforming Growth Factor Beta 2 Expression Journal of Investigative Dermatology · 2005
    29. Effect of Minoxidil on Proliferation and Apoptosis in Dermal Papilla Cells of Human Hair Follicle Journal of Dermatological Science · 2004
    30. Promotion of Hair Growth by Ginseng Radix on Cultured Mouse Vibrissal Hair Follicles Phytotherapy Research · 2003
    31. Effect of Adenovirus-Mediated Expression of Sonic Hedgehog Gene on Hair Regrowth in Mice With Chemotherapy-Induced Alopecia JNCI: Journal of the National Cancer Institute · 2001
    32. A Role for p75 Neurotrophin Receptor in the Control of Apoptosis-Driven Hair Follicle Regression The FASEB Journal · 2000
    33. Conditional Disruption of Hedgehog Signaling Pathway Defines Its Critical Role in Hair Development and Regeneration Journal of Investigative Dermatology · 2000
    34. Finasteride in the Treatment of Men with Androgenetic Alopecia Journal of The American Academy of Dermatology · 1998
    35. Panax Ginseng Prevents Apoptosis in Hair Follicles and Accelerates Recovery of Hair Medullary Cells in Irradiated Mice PubMed · 1998
    36. Bioassay of Crude Drugs for Hair Growth Promoting Activity in Mice by a New Simple Method Planta Medica · 1980

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    3. Hair-Growth Potential of Ginseng and Its Major Metabolites: A Review on Its Molecular Mechanisms International Journal of Molecular Sciences · 2018
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