The Inductive Effect of Ginsenoside F2 on Hair Growth by Altering the WNT Signal Pathway in Telogen Mouse Skin

    Heon-Sub Shin, Sang-Yong Park, Eunson Hwang … Tae-Hoo Yi
    Studysummary This study found that minor ginseng saponin F2 may promote hair growth more effectively than finasteride by enhancing anagen induction and modulating the Wnt signaling pathway in cell and mouse models.
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    Research cited in this study 10

    1. Preventable Effect of L-Threonate, an Ascorbate Metabolite, on Androgen-Driven Balding via Repression of Dihydrotestosterone-Induced Dickkopf-1 Expression in Human Hair Dermal Papilla Cells BMB Reports · 2010
    2. Effect of Citrullus Colocynthis Schrad Fruits on Testosterone-Induced Alopecia Natural Product Research · 2009
    3. Biology of the Hair Follicle: The Basics Seminars in Cutaneous Medicine and Surgery · 2006
    4. Molecular Principles of Hair Follicle Induction and Morphogenesis BioEssays · 2005
    5. Molecular Control of Epithelial-Mesenchymal Interactions During Hair Follicle Cycling ˜The œjournal of investigative dermatology. Symposium proceedings/˜The œJournal of investigative dermatology symposium proceedings · 2003
    6. Expression of ΔNLef1 in Mouse Epidermis Results in Differentiation of Hair Follicles into Squamous Epidermal Cysts and Formation of Skin Tumors Development · 2002
    7. Effects of Finasteride on Apoptosis and Regulation of the Human Hair Cycle Journal of Cutaneous Medicine and Surgery · 2002
    8. Finasteride Increases Anagen Hair in Men with Androgenetic Alopecia British Journal of Dermatology · 2000
    9. Trypsin-Induced Follicular Papilla Apoptosis Results in Delayed Hair Growth and Pigmentation Developmental Dynamics · 1997
    10. The 5 Alpha-Reductase System and Its Inhibitors Dermatology · 1996

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    5. The Inductive Effect of Ginsenoside F2 on Hair Growth by Altering the WNT Signal Pathway in Telogen Mouse Skin European Journal of Pharmacology · 2014
    6. Epithelial Wnt Ligand Secretion Is Required for Adult Hair Follicle Growth and Regeneration Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · 2013
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    8. Natural Scalp Hair Regression in Preclinical Stages of Male Androgenetic Alopecia and Its Reversal by Finasteride Skin Pharmacology and Physiology · 2006