Maintenance of Optimized Hair Growth from Viable Terminal Scalp Hair Follicles at Baseline with Oral Finasteride in Male Pattern Hair Loss and First Evidence of a Drug Dependency and a Post-Finasteride Rebound Effect

    May 2019 in “ Skin Research and Technology ”
    D. Van Neste
    Studysummary This study found that male pattern hair loss worsened significantly after stopping finasteride, revealing a "rebound effect" where terminal hair transformed into miniaturized hair over 30 months off the drug.
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    Research cited in this study 10

    1. Why Care About Linear Hair Growth Rates? A Study Using In Vivo Imaging and Computer-Assisted Image Analysis After Manual Processing in Unaffected Male Controls and Men with Male Pattern Hair Loss European Journal of Dermatology · 2014
    2. Exogen Hair Characterization in Human Scalp Skin Research and Technology · 2007
    3. Natural Scalp Hair Regression in Preclinical Stages of Male Androgenetic Alopecia and Its Reversal by Finasteride Skin Pharmacology and Physiology · 2006
    4. Morphological Approach to Hair Disorders Journal of Investigative Dermatology Symposium Proceedings · 2003
    5. Contrast Enhanced Phototrichogram Pinpoints Scalp Hair Changes in Androgen Sensitive Areas of Male Androgenetic Alopecia Skin Research and Technology · 2002
    6. Measuring Reversal of Hair Miniaturization in Androgenetic Alopecia by Follicular Counts in Horizontal Sections of Serial Scalp Biopsies: Results of Finasteride 1mg Treatment of Men and Postmenopausal Women Journal of Investigative Dermatology Symposium Proceedings · 1999
    7. Finasteride in the Treatment of Men with Androgenetic Alopecia Journal of The American Academy of Dermatology · 1998
    8. Balding Hair Follicle Dermal Papilla Cells Contain Higher Levels of Androgen Receptors Than Those From Non-Balding Scalp Journal of Endocrinology · 1998
    9. Diagnostic and Predictive Value of Horizontal Sections of Scalp Biopsy Specimens in Male Pattern Androgenetic Alopecia Journal of The American Academy of Dermatology · 1993
    10. Natural Progression of Male Pattern Baldness in Young Men Clinical and Experimental Dermatology · 1991

    Related research 9

    1. Male Androgenetic Alopecia CRC Press eBooks · 2021
    2. Pharmacological Therapeutics in Androgenetic Alopecia Journal of The Korean Medical Association · 2020
    3. Maintenance of Optimized Hair Growth from Viable Terminal Scalp Hair Follicles at Baseline with Oral Finasteride in Male Pattern Hair Loss and First Evidence of a Drug Dependency and a Post-Finasteride Rebound Effect Skin Research and Technology · 2019
    4. Hair Loss (Alopecia or Baldness) 2018
    5. Treatments of Hereditary Hair Loss (Alopecia) 2018
    6. Androgenetic Alopecia and Its Remedies: A Review Journal of drug discovery and therapeutics · 2014
    7. Disorders of Hair DeckerMed Medicine · 2013
    8. Characteristics of Korean Scalp Hair and Male Pattern Baldness Journal of The Korean Medical Association · 2013
    9. Androgenetic Alopecia: Pathogenesis and Potential for Therapy Expert Reviews in Molecular Medicine · 2002