Fibroblast Growth Factors Stimulate Hair Growth Through Beta-Catenin and Shh Expression in C57BL/6 Mice

January 2015 in “ BioMed Research International ”

Weihong Lin, Liangzhong Xiang, Hongxue Shi, Jian Zhang, Liping Jiang, Pingtao Cai, Zhenlang Lin, Bin Lin, Yan Huang, Hailin Zhang, Xiaobing Fu, Ding-Jiong Guo, Xiaokun Li, Xiaojie Wang, Jian Xiao

fibroblast growth factors FGF-10 FGF-1 FGF-2 anagen phase β-catenin Sonic hedgehog Shh hair follicles C57BL/6 mice FGFs hair growth growth phase hair follicle development

Studysummary In this study, topical application of fibroblast growth factors was found to promote hair growth by inducing and prolonging the anagen phase in telogenic C57BL/6 mice, suggesting potential as hair growth-promoting agents.

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