7-Phloroeckol Promotes Hair Growth on Human Follicles In Vitro

    May 2014 in “ Naunyn-Schmiedeberg's Archives of Pharmacology ”
    Soon‐Sun Bak, Young Kwan Sung, Se‐Kwon Kim
    Image of study
    TLDR 7-Phloroeckol from brown algae may help hair grow.
    The study from 2014 investigated the effects of 7-phloroeckol, a compound from marine brown algae, on hair growth using human hair follicles in vitro. It was found that 7-phloroeckol significantly increased the proliferation of human dermal papilla cells (DPCs) and outer root sheath (ORS) cells, as well as the elongation of the hair shaft. Additionally, the compound boosted insulin-like growth factor (IGF)-1 mRNA expression and protein concentration in DPCs. The treatment with 7-phloroeckol led to a significant increase in IGF-1 mRNA expression (4.98- and 5.37-fold) and IGF-1 secretion (783 and 841 pg/ml) compared to the control (483 pg/ml), while it did not significantly affect the expression of other growth factors such as VEGF, KGF, and HGF mRNA. These results suggest that 7-phloroeckol has potential as a treatment for hair loss and for promoting hair growth, although the exact number of hair follicles tested was not specified. The research was funded by the Marine Bioprocess Research Center of the Marine Biotechnology Program in Korea.
    Discuss this study in the Community →

    Research cited in this study

    4 / 4 results

    Related Community Posts Join

    6 / 1000+ results

      community 7.5 months post transplant results so far

      in Transplants  440 upvotes 2 weeks ago
      The user shared their 7.5-month post-hair transplant results, mentioning they have been using finasteride and oral minoxidil. The conversation includes mixed reactions, with some users complimenting the results and others critiquing the hairstyle and presentation.

      community 7 months dutasteride minoxidil microneedling 25y.o. Some progress.

      in Progress Pictures  347 upvotes 1 month ago
      A 25-year-old shared progress in hair regrowth after 7 months using dutasteride, minoxidil, and microneedling, noting some baby hair growth on the temples. The user plans to continue this treatment, having found it effective despite some initial shedding and challenges with styling due to topical minoxidil.
      7 Months on Fin + Min + 1 Month Microneedling

      community 7 Months on Fin + Min + 1 Month Microneedling

      in General  113 upvotes 1 month ago
      The user has been using Finasteride and Minoxidil for 7 months and started microneedling a month ago, but is experiencing increased hair shedding and is concerned about its effectiveness. They have vitamin D3 and B12 deficiencies and are seeking advice and encouragement due to a family history of baldness.

      community 7 weeks on 1mg finasteride/1.5mg minoxidil

      in Progress Pictures  10 upvotes 2 months ago
      A 37-year-old male started a hair loss treatment 7 weeks ago using 1mg finasteride, 1.5mg minoxidil, and microneedling, with noticeable coverage improvement except for the right temple. He is considering a hair transplant in the future if needed.

      community 7 day break from Fin in order to donate blood?

      in General  143 upvotes 3 months ago
      A user needs to stop finasteride for 7 days to donate blood due to haemochromatosis. They are concerned if this break will affect their hair loss progress after 6 weeks of use.

    Related Research

    5 / 5 results