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    Glossary Insulin-like Growth Factor

    protein promoting cell growth and development, similar to insulin

    Insulin-like Growth Factor (IGF) refers to a group of proteins with a structure similar to insulin that play a crucial role in growth and development, particularly during childhood. IGF is involved in cell growth, differentiation, and survival, and it is primarily produced in the liver in response to growth hormone stimulation. It has significant implications in various biological processes, including muscle growth, bone development, and even hair follicle health.

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    1. Role of insulin, insulin‐like growth factor‐1, hyperglycaemic food and milk consumption in the pathogenesis of acne vulgaris Experimental dermatology · 2009 · 200 citations
    2. Androgen Induction of Follicular Epithelial Cell Growth Is Mediated via Insulin-like Growth Factor-I from Dermal Papilla Cells Biochemical and biophysical research communications · 1995 · 173 citations
    3. Overexpression of insulin-like growth factor-1 induces hyperplasia, dermal abnormalities, and spontaneous tumor formation in transgenic mice Oncogene · 1997 · 147 citations
    4. Insulin-like growth factor 1 and hair growth Dermatology Online Journal · 1999 · 98 citations
    5. Skin expression of mammalian target of rapamycin and forkhead box transcription factor O1, and serum insulin‐like growth factor‐1 in patients with acne vulgaris and their relationship with diet British Journal of Dermatology · 2016 · 93 citations
    6. Differential effects of caffeine on hair shaft elongation, matrix and outer root sheath keratinocyte proliferation, and transforming growth factor‐β2/insulin‐like growth factor‐1‐mediated regulation of the hair cycle in male and female human hair follicles<i>in vitro</i> British Journal of Dermatology · 2014 · 60 citations
    7. The expression of insulin-like growth factor 1 in follicular dermal papillae correlates with therapeutic efficacy of finasteride in androgenetic alopecia Journal of The American Academy of Dermatology · 2003 · 49 citations
    8. Cortisol Enhances the Expression of mac25/Insulin-Like Growth Factor-Binding Protein-Related Protein-1 in Cultured Osteoblasts**This work was supported by NIDDK Grant DK-45227 and a scholarship (to R.C.P.) from Fundacao Coordenacao de Aperfeicoa mento de Pessoal de Nivel Superior (CAPES), Universidade de Sao Paulo (Sao Paulo, Brazil). Endocrinology · 1999 · 43 citations
    9. Induction of Hair Growth by Insulin-Like Growth Factor-1 in 1,763 MHz Radiofrequency-Irradiated Hair Follicle Cells PLoS ONE · 2011 · 39 citations
    10. Effect of topical application of raspberry ketone on dermal production of insulin-like growth factor-I in mice and on hair growth and skin elasticity in humans Growth hormone & IGF research · 2008 · 39 citations
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    Community 9 of 39

    1. Anyone here in the 0% like me? Reddit · 19 Mar 2024
    2. Increasing GH and IGF-1 for Increased Growth/Reduced Hair Loss? Reddit · 10 Oct 2023
    3. Best, possible, or experimental growth agonists that AREN'T MINOXIDIL. Reddit · 31 Dec 2020
    4. IGF-1 and Peptides? Miracle molecule waiting to be found Reddit · 1 Sept 2025
    5. Hairloss - what hormones to check? Reddit · 20 Dec 2023
    6. So what’s really the deal with dutasteride hairline ruining claims? Reddit · 3 Oct 2022
    7. Fin isn’t working anymore after 3 years, afraid to switch to dut? Reddit · 26 Jul 2024
    8. A science based addition to your hair loss routine Reddit · 4 Jul 2024
    9. Female, 30, PCOS diagnosis, MPB Norwood 2. Endo refuses to give anything other than Spironolactone. Feel like I’m at my wit’s end here. Reddit · 19 Nov 2023
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