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GlossaryKeratinocyte Growth Factor (KGF)

stimulates skin and hair cell growth and repair

Keratinocyte Growth Factor (KGF), also known as Fibroblast Growth Factor 7 (FGF-7), is a protein that plays a crucial role in the growth and repair of skin and hair. It specifically stimulates the proliferation and differentiation of keratinocytes, which are the primary cells found in the outer layer of the skin and hair follicles. This makes KGF important in wound healing and potentially beneficial in treating conditions like alopecia.

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research KGF And EGF Signaling Block Hair Follicle Induction And Promote Interfollicular Epidermal Fate In Developing Mouse Skin

82 citations, May 2009 in “Development”

EGF and KGF signalling prevent hair follicle formation and promote skin cell development in mice.

Hair Growth Induction by the Tellurium Immunomodulator AS101: Association with Delayed Terminal Differentiation of Follicular Keratinocytes and Ras-Dependent Up-Regulation of KGF Expression

research Hair Growth Induction by the Tellurium Immunomodulator AS101: Association with Delayed Terminal Differentiation of Follicular Keratinocytes and Ras-Dependent Up-Regulation of KGF Expression

51 citations, December 2003 in “The FASEB Journal”

The substance AS101 can help hair grow by slowing down hair cell aging and boosting a hair growth protein.

research The Role of the VEGF, KGF, EGF, and TGF-β1 Growth Factors in the Pathogenesis of Telogen Effluvium in Women

5 citations, March 2017 in “Biomedical and Pharmacology Journal”

Certain growth factors significantly affect hair loss in women with telogen effluvium.

research FCP 3: Platelet-Rich Plasma Induced Hair Growth in Alopecia Patients Partially Through Dermal Papilla Cell Proliferation, BCl-2 and KGF Up-Regulation

January 2014 in “프로그램북(구 초록집)”

Platelet-rich plasma treatments help hair growth in people with hair loss by increasing certain cell growth and protein levels.

research Expression and Function of Keratinocyte Growth Factor and Activin in Skin Morphogenesis and Cutaneous Wound Repair

113 citations, December 2000 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings”

KGF and activin are crucial for skin healing and repair.

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community Opinions on this study for Triphasic Progressive by Rene Furterer

in Research/Science 14 upvotes 1 year ago

The user shared their 5-year hair loss journey, initially using a product called Triphasic Progressive by Rene Furterer, which gave good results. Later, they switched to FDA-approved medications finasteride and minoxidil, which also helped, but they noticed the most significant progress with Triphasic. They're considering trying it again if minoxidil doesn't show improvements.

community SAFFLOWER OIL good alternative for Minoxidil?

in Treatment 1 upvotes 4 years ago

Safflower oil is suggested as an alternative to minoxidil for hair growth, with benefits including scalp conditioning and hair strength enhancement. Studies indicate it may also reverse scalp dermatitis, alopecia, and prevent premature grayness.

community Wtf have we been doing for the last 30 years

in Treatment 526 upvotes 3 days ago

Hair loss treatments like finasteride, minoxidil, and dutasteride work but have side effects. A permanent cure is still not available due to the complexity of hair loss and limited investment.