Prostanoids and Hair Follicles: Implications for Therapy of Hair Disorders
November 2017
in “
Acta dermato-venereologica
”
Studysummary This review examines how different prostanoids and their receptors affect hair growth but provides no new clinical results; it highlights potential implications for treating hair disorders. Our plain-language summary of this paper — not a Tressless recommendation.
The paper "Prostanoids and Hair Follicles: Implications for Therapy of Hair Disorders" by Xu and Chen from 2017 reviewed the role of prostanoids, including prostaglandins (PGs) and thromboxane A2 (TXA2), in regulating hair growth. The authors highlighted that the PGF2α analogue, approved by the FDA, is used to enhance human eyelash growth. PGE2 was reported to protect against radiation-induced hair loss in mice. However, PGD2 was found to inhibit hair growth. The paper emphasized the potential clinical relevance of understanding the metabolism of prostanoids and the expression pattern of prostanoid receptors in hair follicles for the treatment and prevention of hair disorders.
