Setipiprant/PGE2 feedbacks?
    5/10/2018

    From the encyclopedia
    Minoxidil →

    An essential vasodilator with some anti-androgenic effects

    At a glance
    In this question or advice post, the primary subjects mentioned are
    💧 PGE2 (topical) 100 micrograms/ml 2ml daily
    💊 Setipiprant (oral)
    💧 Minoxidil (topical)
    the tone is 😐 neutral.

    Other terms

    The conversation discusses using PGE2 as a hair growth stimulant, comparing it to minoxidil, and considering the addition of Setipiprant. Concerns about side effects like skin damage and cost are also mentioned.
    View this post in the Community →

    Similar Community Posts Join

    5 / 5 results

      community Best, possible, or experimental growth agonists that AREN'T MINOXIDIL.

       4 upvotes 5 years ago
      Various hair growth treatments were discussed, including microneedling, bimatoprost, setipiprant, stemoxydine, PGE2, CB-03-01, WNT Beta-Catenin upregulators, KY19382, topical estrogen, IGF-1, GH, MK-677, oral castor oil, fisetin, resveratrol, cetrizine, and lactic acid. Users shared experiences and sources for these treatments, with some expressing interest in topical solutions and others noting the lack of FDA approval or scientific evidence for certain options.

      community Why not Travopost? More effective than min, and stackable.

      in Research/Science  18 upvotes 1 year ago
      Travoprost may be more effective than minoxidil for hair growth and can be used alongside it, but its effectiveness is debated due to inconsistent dosing results. Travoprost is expensive and not widely used, with alternatives like latanoprost and bimatoprost being more accessible.

      community Anyone here has experience with ‘nuke’ protocols?

       4 upvotes 5 years ago
      The conversation discusses aggressive hair loss treatments, including finasteride, dutasteride, minoxidil, topical cetirizine, and experimental options like Estrogel, oh-flutamide, and RU58841. Users share experiences and suggest trying oral minoxidil and el cranell, noting the complexity and challenges of treating hair loss.

      community DLQ01: A Better "Minoxidil" PGF2a synthetic analogue.

       3 upvotes 1 year ago
      DLQ01, a prostaglandin F2α analog, shows promise for hair growth by directly stimulating PGE2/PGF receptors without needing conversion, and can be combined with minoxidil and retinoids like tretinoin for enhanced effectiveness. Minoxidil's efficacy may be reduced by COX-1 inhibitors, but using prostaglandin analogs like Latanoprost or Bimatoprost can help maintain its effectiveness.

      community Painkillers May Block Minoxidil

       12 upvotes 1 year ago
      Painkillers like Aspirin may reduce Minoxidil's effectiveness by inhibiting the enzyme PGHS-1, which is crucial for hair growth. Using NSAIDs that inhibit COX-2 or combining Minoxidil with PGF2/E2 analogues or retinoids may enhance its efficacy.

    Related Research

    6 / 6 results
      Androgenetic Alopecia: An Update Of Treatment Options

      research Androgenetic Alopecia: An Update of Treatment Options

      110 citations , August 2016 in “Drugs”
      Minoxidil is the only FDA-approved topical drug for treating male or female pattern hair loss, and other medications like finasteride and dutasteride can also increase hair growth.
      Experimental and Early Investigational Drugs for Androgenetic Alopecia

      research Experimental and early investigational drugs for androgenetic alopecia

      11 citations , July 2017 in “Expert Opinion on Investigational Drugs”
      This review discusses current and emerging therapeutic strategies for androgenetic alopecia, noting limited evidence but suggesting areas such as prostaglandin analogs, PRP, and progenitor cell therapies as promising future directions.
      Treatment Options for Alopecia

      research Treatments options for alopecia

      17 citations , August 2015 in “Expert Opinion on Pharmacotherapy”
      This article discusses the social and psychological impact of hair disorders and the challenges in their treatment, but reports no new clinical results.
      A Review of the Treatment of Male Pattern Hair Loss

      research A review of the treatment of male pattern hair loss

      53 citations , February 2020 in “Expert Opinion on Pharmacotherapy”
      This review discusses pharmacologic and non-pharmacologic treatments for androgenetic alopecia, noting that current medications like finasteride and minoxidil can slow hair loss but only partially restore hair growth, with early treatment offering better outcomes.