Comprehensive Review on Hair Loss and Restorative Techniques: Advances in Diagnostic, Artistry, and Surgical Innovation

    April 2025 in “ Cureus
    Luis A Mendoza, Genaro G Ocampo, Yozahandy A Abarca-Pineda, Mohamed F. R. Khan, Yasmin Ahmadi, Najaee Brown, Denyse Deowan, Zahra Nazir
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    TLDR Advancements in diagnostics, treatments, and technology have improved hair loss detection and restoration, with some types being reversible.
    The review highlights significant advancements in diagnosing and treating hair loss, categorizing alopecia into cicatricial and non-cicatricial types, with non-scarring alopecia being potentially reversible. Diagnostic tools like trichoscopy and AI-based systems have improved early detection, while innovations such as robotic systems and stem cell therapies have enhanced treatment outcomes. Pharmacological treatments like minoxidil and 5-alpha reductase inhibitors show efficacy, though side effects and the need for further research are noted. Non-invasive treatments like low-level laser therapy and platelet-rich plasma therapy are effective in increasing hair density. Surgical techniques, particularly Follicular Unit Transplantation and Follicular Unit Extraction, have advanced, with AI-assisted robotic technology improving precision. The review underscores the importance of combining functionality with artistry in hair restoration and calls for further research to standardize protocols and optimize outcomes.
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      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 10 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community I am a dermatologist with a clinical interest in alopecia. AMA

      in Will treatment work for me? 2 years ago
      In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

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