Review of Oral Minoxidil as Treatment of Hair Disorders: In Search of the Perfect Dose

    March 2021
    Alberto Villani, Gabriella Fabbrocini, Jorge Ocampo-Candiani, Antonio Ruggiero, Jorge Ocampo-Candiani
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    TLDR Oral minoxidil effectively treats hair loss, with women needing lower doses (0.25 to 2.5 mg daily) and men needing higher doses (1.25 to 5 mg daily).
    The review article discusses the use of oral minoxidil as a treatment for various hair disorders, including androgenetic alopecia, telogen effluvium, tractional alopecia, and others. The authors concluded that oral minoxidil is a successful and well-tolerated treatment for hair loss, with dosages varying from 0.25 to 5 mg daily. Women typically require lower doses (0.25 to 2.5 mg daily), while men require higher doses (1.25 to 5 mg daily) for maximal efficacy. The largest study cited involved 18,918 male patients with androgenetic alopecia, who showed significant improvement with a combination treatment including oral minoxidil. However, the authors recommend larger randomized comparative studies to clarify the best treatment protocol, including dosage and treatment duration.
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      community C’est terrible - at my wits end

      in Female  443 upvotes 1 year ago
      A 29-year-old woman is experiencing gradual hair thinning since age 15, suspects Androgenic Alopecia, and has tried 5% minoxidil with little success. She has purchased various hair loss treatments including minoxidil, dutasteride, finasteride, and spironolactone, but is cautious about starting them due to potential interactions with her ADHD medication.

      community Anyone here in the 0% like me?

      in Finasteride/Dutasteride  42 upvotes 8 months ago
      The user has tried topical minoxidil, oral minoxidil, finasteride, RU58841, and dermapen for over a year without seeing hair regrowth and has now switched to dutasteride, planning to continue until summer. Some responses suggest that no further hair loss could be considered progress, question the visibility of hair loss, and recommend trying vitamin D.

      community Why balding gets worse in every generation?

      in Chat  81 upvotes 5 months ago
      Balding seems to worsen with each generation, possibly due to stress, diet, and environmental factors. The user started treatments like Minoxidil and finasteride.

      community I am a dermatologist with a clinical interest in alopecia. AMA

      in Will treatment work for me? 2 years ago
      In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

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