Physiopathology and Current Treatments of Androgenetic Alopecia: Going Beyond Androgens and Anti-Androgens

    September 2019 in “ Dermatologic Therapy
    Tatiele Katzer, Ademir Carvalho Leite Júnior, Ruy Carlos Ruver Beck, Cristiane B. da Silva
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    TLDR Hair loss treatments work better with lifestyle changes.
    This article discusses the physiopathology and current treatments of androgenetic alopecia (AGA), a genetic condition that causes hair loss. AGA is caused by a combination of factors, including inflammation, oxidative stress, aging, smoking, UV radiation, pollutants, and lifestyle choices. The article discusses various treatments for AGA, including finasteride, minoxidil, and dutasteride, and their mechanisms of action. The article also emphasizes the importance of behavior modification to decrease the extent of clinical manifestations. The article suggests that combining different strategies, substances with synergic mechanisms, and the use of advantageous technologies associated with lifestyle changes could improve treatment outcomes.
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