TLDR VEGF and its receptor might cause hair loss.
This article suggests that vascular endothelial growth factor (VEGF) and its receptor may be a molecular mechanism for androgenetic alopecia (AGA). Dihydrotestosterone (DHT) binds to androgen receptors in hair follicles, down-regulating the expression of VEGF in dermal papilla cells (DPC), which leads to hair loss. The document also briefly mentions the role of serotonin in viral hepatitis and proposes a modification to the rapid tryptophan depletion (RTD) procedure to potentially reduce virus persistence and immunopathology.
397 citations
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February 2004 in “British Journal of Dermatology” Minoxidil boosts hair growth by opening potassium channels and increasing cell activity.
14 citations
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December 2003 in “Medical Hypotheses” Male-pattern baldness might be caused by the effect of hormones on scalp blood vessels.
47 citations
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May 1995 in “Journal of Investigative Dermatology” Hair follicles in people with alopecia have lower levels of a key blood vessel growth protein.
May 2025 in “Scientific Reports” Oxyresveratrol promotes hair growth and may help treat hair loss.
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4 citations
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September 2020 in “Frontiers in Microbiology” Algal oligosaccharides help prevent hair loss and promote hair growth.
5 citations
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25 citations
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May 2020 in “Stem Cells Translational Medicine” ADSC-CE treatment safely increases hair density and thickness in androgenetic alopecia patients.
