TLDR VEGF and its receptor might cause hair loss.
This article suggests that vascular endothelial growth factor (VEGF) and its receptor may be a molecular mechanism for androgenetic alopecia (AGA). Dihydrotestosterone (DHT) binds to androgen receptors in hair follicles, down-regulating the expression of VEGF in dermal papilla cells (DPC), which leads to hair loss. The document also briefly mentions the role of serotonin in viral hepatitis and proposes a modification to the rapid tryptophan depletion (RTD) procedure to potentially reduce virus persistence and immunopathology.
397 citations,
February 2004 in “British Journal of Dermatology” Minoxidil boosts hair growth by opening potassium channels and increasing cell activity.
14 citations,
December 2003 in “Medical Hypotheses” Male-pattern baldness might be caused by the effect of hormones on scalp blood vessels.
47 citations,
May 1995 in “Journal of Investigative Dermatology” Hair follicles in people with alopecia have lower levels of a key blood vessel growth protein.
February 2021 in “International journal of regenerative medicine” A new method using fat tissue cells may help treat hair loss.
4 citations,
September 2020 in “Frontiers in Microbiology” Algal oligosaccharides help prevent hair loss and promote hair growth.
5 citations,
March 2018 in “Clinics in Dermatology” PRP injections and scalp lifting together improve hair thickness and growth in hair loss patients.
25 citations,
May 2020 in “Stem Cells Translational Medicine” ADSC-CE treatment safely increases hair density and thickness in androgenetic alopecia patients.
Androgenetic alopecia, or hair loss, is caused by genetic factors and hormones, with different mechanisms in men and women, and can be linked to insulin resistance and polycystic ovary syndrome.
