Infranatant Portion of Microfragmented Adipose Tissue: A Promising Source of Stromal Vascular Fraction for the Management of Androgenetic Alopecia

    Alessandro Gennai, Piero Tesauro, Mattia Colli, Silvia Zia, Barbara Roda, Andrea Zattoni
    TLDR A new method using fat tissue cells may help treat hair loss.
    The study demonstrated that the infranatant portion of emulsified microfragmented adipose tissue (EMU), obtained using the SEFFIHAIR™ device, contained a higher number of viable stromal vascular fraction (SVF) cells compared to non-emulsified tissue. This method, which involved mechanical digestion and did not require enzymatic digestion, liberated more alive and proliferating cells, particularly in the infranatant. The findings suggested that this minimally invasive technique could be a promising and effective therapy for managing androgenetic alopecia (AGA) by decelerating or reversing hair follicle miniaturization through the anti-inflammatory and anti-fibrotic properties of adipose-derived stem cells (ADSCs). Further research was recommended to better understand the cell population and its potential in regenerative medicine.
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