Study of the Efficacy of Carboxytherapy in Alopecia

The study from 2018 assessed the effectiveness and safety of carboxytherapy, which involves injecting carbon dioxide gas, in treating 80 patients with alopecia areata (AA) and androgenetic alopecia (AGA). Patients were divided into groups, with half receiving carboxytherapy and half receiving a placebo, and followed for 3 months. Results indicated that carboxytherapy led to significant clinical and dermoscopic improvements in both AA and AGA patients compared to placebo, with increased hair density and regrowth. However, these effects regressed after treatment stopped, suggesting the need for ongoing sessions and possibly additional treatments. Side effects were minimal and transient. The study concluded that carboxytherapy could be a promising adjuvant therapy for AA and AGA, but more research is needed to confirm these findings.