Apoptosis in Follicles of Individuals with Female Pattern Hair Loss Is Associated with Perifollicular Microinflammation

May 2016 in “ International Journal of Cosmetic Science ”

Pablo Ramos, Gabrielli Brianezi, Alfredo Martins, M. Fátima C. Guedes da Silva, M. Matilde Marques, Hélio Amante Miot

apoptosis hair follicles female pattern hair loss perifollicular microinflammation inflammation follicle miniaturization cell death FPHL

TLDR Hair loss in women links to inflammation around hair follicles.

This study found that apoptosis (cell death) in hair follicles of individuals with female pattern hair loss (FPHL) is associated with perifollicular microinflammation. The study involved 17 women with FPHL and five controls, and showed that inflammation can lead to apoptosis and play a role in the pathogenesis of follicle miniaturization. The study highlights the importance of understanding the role of inflammation in FPHL and the need for further research to confirm this mechanism.

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Research cited in this study

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Apoptosis in Follicles of Individuals with Female Pattern Hair Loss Is Associated with Perifollicular Microinflammation

Research cited in this study

research The Impact of Oxidative Stress on Hair

research Female Pattern Hair Loss: A Clinical and Pathophysiological Review

research Factors Associated With Female Pattern Hair Loss And Its Prevalence In Taiwanese Women: A Community-Based Survey

research Hair Through the Female Life Cycle

research Evaluation of Apoptosis Regulatory Markers in Androgenetic Alopecia

research Effects of Finasteride on Apoptosis and Regulation of the Human Hair Cycle

research Androgenetic Alopecia and Microinflammation

research Diagnostic and Predictive Value of Horizontal Sections of Scalp Biopsy Specimens in Male Pattern Androgenetic Alopecia

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