The Action of a Cosmetic Hair Treatment on Follicle Function

March 2018 in “ bioRxiv (Cold Spring Harbor Laboratory) ”

G. A. Turner, Paterson Se, Baines Fl, Andrew E. Mayes, Reilly Dm, Hudson Nm, Tony Dadd, A.K. Majumdar, Rinky Kapoor, Jieruo Gu, Needhi Bhalla, Fang Xu

Dynagen zinc salts hair growth fiber diameter follicle-cell proliferation plucking force claudin-1 protease activity Dynagen TM

Studysummary In this study, a new leave-on hair treatment with Dynagen and zinc salts significantly increased hair growth rate, fibre diameter, and follicle strength in healthy women. Our plain-language summary of this paper — not a Tressless recommendation.

The document reports on a series of studies that investigated the effects of a new leave-on hair treatment (LOT) containing Dynagen TM and zinc salts on hair growth. The studies involved healthy women aged 18–65 and used various methods to assess the LOT's impact on hair growth rate, fiber diameter, follicle-cell proliferation, and plucking force. Results showed that the LOT significantly increased hair growth rate, fiber diameter, bundle cross-sectional area, and the plucking force required to remove hair, indicating stronger follicular root structure. Additionally, Dynagen was found to increase claudin-1 expression in cultured follicles, and zinc salts reduced protease activity. Overall, the Dynagen-based LOT was concluded to enhance hair-fiber diameter and growth rate, as well as strengthen the hair follicle.

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