Evaluation of Apoptosis Regulatory Markers in Androgenetic Alopecia

December 2010 in “ Journal of Cosmetic Dermatology ”

Moetaz El-Domyati, Sameh Attia, Fatma M. Saleh, Mohamed Bassyouni, Manal Barakat, Hossam Abdel-Wahab

androgenetic alopecia apoptosis hair follicles follicular miniaturization DNA damage proliferation rate AGA

TLDR Apoptosis may contribute to hair loss in androgenetic alopecia.

This study evaluated the role of apoptosis regulatory markers in androgenetic alopecia (AGA) by examining the expression of various markers in the hair follicles of AGA patients and normal controls. The study found that the bald area of AGA has a lower proliferation rate and increased DNA damage, which may result in increased apoptosis and follicular miniaturization. The study suggests that apoptosis may play a role in the pathogenesis of AGA, but further studies are needed to confirm this.

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research Proliferation, DNA Repair, and Apoptosis in Androgenetic Alopecia

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Bald areas have lower cell growth, more DNA damage, and increased cell death.

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