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    Penetration and Storage of Particles in Human Skin: Perspectives and Safety Aspects

    April 2011 in “ European Journal of Pharmaceutics and Biopharmaceutics ”
    Juergen Lademann, Heike Richter, Sabine Schanzer … Alexa Patzelt
    Studysummary This review discusses the mechanisms and storage of particles in hair follicles and presents no new experimental results, highlighting the need for further research in their safe application in dermatology and cosmetics.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 11

    1. Selective Follicular Targeting by Modification of the Particle Sizes Journal of Controlled Release · 2011
    2. Determination of the Cuticle Thickness of Human and Porcine Hairs and Their Potential Influence on the Penetration of Nanoparticles into the Hair Follicles Journal of Biomedical Optics · 2009
    3. Hair Follicles, Their Disorders, and Their Opportunities Drug Discovery Today: Disease Mechanisms · 2008
    4. Imaging of Zinc Oxide Nanoparticle Penetration in Human Skin In Vitro and In Vivo Journal of biomedical optics · 2008
    5. Investigation of Differences in Follicular Penetration of Particle- and Nonparticle-Containing Emulsions by Laser Scanning Microscopy Laser Physics · 2006
    6. 40nm, But Not 750 or 1,500nm, Nanoparticles Enter Epidermal CD1a+ Cells After Transcutaneous Application on Human Skin ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2006
    7. Follicular Targeting: A Promising Tool in Selective Dermatotherapy ˜The œjournal of investigative dermatology. Symposium proceedings/˜The œJournal of investigative dermatology symposium proceedings · 2005
    8. Transfollicular Drug Delivery: Is It a Reality? International journal of pharmaceutics · 2005
    9. Differential Stripping: Determination of the Amount of Topically Applied Substances Penetrated into the Hair Follicles ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2005
    10. Penetration Profile of Microspheres in Follicular Targeting of Terminal Hair Follicles ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2004
    11. Variations of Hair Follicle Size and Distribution in Different Body Sites Journal of Investigative Dermatology · 2004