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research A Simple Non-Invasive Approach toward Efficient Transdermal Drug Delivery Based on Biodegradable Particulate System

48 citations , April 2019 in “ACS Applied Materials & Interfaces”

In this study, researchers introduced calcium carbonate-based carriers for transdermal drug delivery, observing efficient transport of substances and systemic absorption in rats, suggesting potential applications in regenerative medicine and dermatology beyond conventional topical treatments.

research Penetration and storage of particles in human skin: Perspectives and safety aspects

122 citations , April 2011 in “European Journal of Pharmaceutics and Biopharmaceutics”

This review discusses the mechanisms and storage of particles in hair follicles and presents no new experimental results, highlighting the need for further research in their safe application in dermatology and cosmetics.

research Nanotechnology in Cosmetics: An Overview

November 2024 in “International Journal of Research and Review”

This review explores the application of nanotechnology in cosmetics, highlighting its role in enhancing skin penetration, sustaining drug action, and protecting against UV radiation, while also addressing regulatory considerations and potential exposure routes.

research Applications of Nanostructured Lipid Carriers: Recent Advancements and Patent Review

17 citations , April 2021 in “Biointerface Research in Applied Chemistry”

This review discusses nanostructured lipid carriers and their potential applications in pharmaceuticals and food, offering no new clinical findings but highlighting recent advancements and patents.

research Patents on Nanoparticulate Drug Delivery Systems - A Review

5 citations , January 2008 in “Recent Patents on Drug Delivery & Formulation”

This review compiles patents for nanoparticulate drug delivery systems, discussing preparation methods, therapeutic applications, and commercialization, but reports no new experimental results.

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community PP405 Won't Work Long Term: Hair Follicle Damage Due to Abuse of the ISR System

67 upvotes 11 months ago

PP405 may damage hair follicles if used long-term, suggesting cycling might be necessary. Combining it with finasteride could help maintain hair growth.

community Everyone is ignoring that plasma finasteride levels are 100x lower with topical compared to oral.

in Research/Science 140 upvotes 2 years ago

Topical finasteride results in plasma levels 100 times lower than oral finasteride, potentially reducing systemic side effects. Users report similar efficacy with fewer side effects, suggesting a preference for topical application.

community Why everyone should be using topical Dutasteride

45 upvotes 3 months ago

Topical Dutasteride, especially in a liposomal base, is recommended for enhanced scalp DHT suppression when used with oral Dutasteride. It is suggested to apply it twice a week for effective results without significant systemic impact.

community Are there ever going to be any oral DHT blocking treatments in the future?

5 upvotes 2 years ago

The discussion revolves around the need for future oral DHT blockers for hair loss treatment that don't have the side effects of current options like Finasteride and Dutasteride. One user suggests that the future of hair loss treatment will likely be topical anti-androgens, as they can target hair follicles without affecting the entire system.

community Bryan Johnson shares information on his hair loss stack

in Research/Science 267 upvotes 1 year ago

Bryan Johnson uses topical dutasteride, minoxidil, and microneedling for hair loss. Users discuss treatment effectiveness and side effects, debating topical versus oral dutasteride efficacy.

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