Selective Follicular Targeting by Modification of the Particle Sizes

February 2011 in “ Journal of Controlled Release ”

Alexa Patzelt, Heike Richter, Fanny Knorr, U. Schäfer, Claus‐Michael Lehr, Lars Dähne, Wolfram Sterry, Juergen Lademann

hair follicles PLGA silica keratin cells terminal hair follicles vellus hair follicles therapeutic substances cosmetic substances

Studysummary This study found that medium-sized particles (643 and 646 nm) penetrated deeper into porcine hair follicles in vitro than smaller or larger particles, suggesting size-selective targeting within follicular sites.

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