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    GlossaryHair Follicles (follicular structures)

    small skin structures from which hair grows

    Hair follicles are small, tunnel-like structures in the skin from which hair grows. Each follicle anchors a single hair into the skin and is composed of several layers, including the bulb at the base where cells divide and grow to build the hair shaft. These structures also contain sebaceous glands that produce oil to condition the hair and skin.

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      learn GHK-Cu

      a copper peptide showing promise in both regrowth and reversing gray hair

      learn HMI-115

      much-hyped research compound targeting prolactin receptor in scalp

      learn Caffeine

      the stimulant you know and love can be used topically to stimulate hair

      learn Minoxidil

      An essential vasodilator with some anti-androgenic effects, has excellent safety record

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      community DHT Harms Scalp Microbiome: DHT Itch is REAL

      in Research/Science  413 upvotes 1 week ago
      Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 8 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Verteporfin and Microneedling

      in Treatments 10 months ago
      Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.