A Link Between Psychiatric Disorders and Non-Scarring Alopecias: A Systematic Review

    November 2022 in “ Skin health and disease ”
    Ana L. Forneris Crego, Anastasia Therianou, Parastoo Hashemi, Claire A. Higgins
    Studysummary This systematic review found a significant association between hair loss and mental health disorders such as major depressive disorder and anxiety, but it was unable to specify correlations for each type of hair loss.
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    Research cited in this study 20

    1. Corticosterone Inhibits GAS6 to Govern Hair Follicle Stem-Cell Quiescence Nature · 2021
    2. Hyperactivation of Sympathetic Nerves Drives Depletion of Melanocyte Stem Cells Nature · 2020
    3. The Psychosocial Burden of Alopecia Areata and Androgenetic Alopecia: A Cross-Sectional Multicentre Study Among Dermatological Outpatients in 13 European Countries Journal of the European Academy of Dermatology and Venereology · 2019
    4. Pathomechanisms of Immune-Mediated Alopecia International Immunology · 2019
    5. HRQoL in Hair Loss-Affected Patients with Alopecia Areata, Androgenetic Alopecia, and Telogen Effluvium: The Role of Personality Traits and Psychosocial Anxiety Journal of The European Academy of Dermatology and Venereology · 2018
    6. The Tendency Towards the Development of Psychosexual Disorders in Androgenetic Alopecia According to the Different Stages of Hair Loss: A Cross-Sectional Study Anais Brasileiros De Dermatologia · 2018
    7. A Mixed Methods Survey of Social Anxiety, Anxiety, Depression, and Wig Use in Alopecia BMJ open · 2017
    8. An Overview of Alopecias Cold Spring Harbor Perspectives in Medicine · 2014
    9. The Difficult Hair Loss Patient: A Particular Challenge International Journal of Trichology · 2013
    10. Hair Loss Perception and Symptoms of Depression in Female Outpatients Attending a General Dermatology Clinic Anais Brasileiros de Dermatologia · 2012
    11. Evaluation of Anxiety and Levels of Serum B12, Folate, TSH, Ferritin, and Zinc in Telogen Alopecia Patients with Trichodynia International Journal of Trichology · 2012
    12. Psychological Interventions in the Management of Common Skin Conditions Psychology Research and Behavior Management · 2010
    13. Neuroimmunology of Stress: Skin Takes Center Stage Journal of Investigative Dermatology · 2006
    14. Hair Growth Inhibition by Psychoemotional Stress: A Mouse Model for Neural Mechanisms in Hair Growth Control Experimental Dermatology · 2005
    15. Stress Exposure Modulates Peptidergic Innervation and Degranulates Mast Cells in Murine Skin Brain Behavior and Immunity · 2004
    16. Burden of Hair Loss: Stress and the Underestimated Psychosocial Impact of Telogen Effluvium and Androgenetic Alopecia Journal of Investigative Dermatology · 2004
    17. The Presence of Trichodynia in Patients With Telogen Effluvium and Androgenetic Alopecia International Journal of Dermatology · 2003
    18. Stress Inhibits Hair Growth in Mice by Inducing Premature Catagen Development and Harmful Perifollicular Inflammatory Events via Neuropeptide Substance P-Dependent Pathways American Journal of Pathology · 2003
    19. Psychological Features of Androgenetic Alopecia Journal of the European Academy of Dermatology and Venereology · 2002
    20. Psychological Characteristics of Women with Androgenetic Alopecia: A Controlled Study British Journal of Dermatology · 1991

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    3. Efficacy of Systemic Minoxidil and Tofacitinib Combination in Treatment-Resistant Alopecia Universalis Journal of Cosmetic Dermatology · 2020
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    8. Diagnosis of Hair Loss: Clinical Features of Common Causes PubMed · 1992
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