Koilonychia in a Patient with Alopecia Areata
February 2021
in “
PubMed
”
TLDR Koilonychia in alopecia areata can improve with oral corticosteroids.
Alopecia areata (AA) is an autoimmune condition that causes hair loss and is often accompanied by nail changes, with a prevalence of 30%. These changes, including koilonychia or "spoon nails," are linked to lymphocytic inflammation and a loss of immune privilege in hair follicles and nail apparatus. Koilonychia is typically associated with iron deficiency and inflammatory skin conditions, but its occurrence with AA is rare and not well-documented in English literature. The case of a 25-year-old female with AA focalis and koilonychia showed significant improvement after treatment with oral corticosteroids, highlighting the need for further exploration of the pathogenesis and prognostic implications of koilonychia in AA.