139 citations
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October 2005 in “Journal of Investigative Dermatology” This study describes previously unknown immune characteristics of the normal human nail, highlighting its similarities to the hair follicle immune system and suggesting an immune privilege in the proximal nail matrix that both provides autoimmunity protection and presents infection susceptibility.
13 citations
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April 2009 in “Journal der Deutschen Dermatologischen Gesellschaft” This article reviews nail involvement in various skin diseases, such as psoriasis and lichen planus, and highlights characteristic changes but reports no new clinical findings.
2 citations
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February 2021 in “PubMed” This case report describes a 25-year-old woman with alopecia areata and nail spooning, which regressed almost completely after treatment with oral corticosteroids.
This study found that the nail immune system is similar to the hair follicle immune system, with both showing a relative "immune privilege" that may protect against autoimmunity.
21 citations
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January 2005 in “Skinmed” This article reviews the structural similarities and common disorders of hair and nails, highlighting their joint involvement in congenital and acquired conditions, but it reports no new clinical results.