Phototherapy for Alopecia Areata

    September 2016 in “ Clinics in dermatology
    Oliverio Welsh
    TLDR Phototherapy can help treat hair loss in alopecia areata.
    The review discussed the use of various phototherapy modalities, including broadband UVB, narrowband UVB, excimer laser, excimer lamp, PUVA, and UVA-1, in treating alopecia areata (AA). Phototherapy worked by modulating the immune response and showed potential as an alternative treatment for patients who were unsuitable for or resistant to conventional therapies like corticosteroids and minoxidil. Studies highlighted included a retrospective study of 25 patients using narrowband UVB, a study of 149 patients using topical PUVA, and a report on 16 patients using a 308-nm excimer lamp, with varying degrees of success in hair regrowth. Despite some positive outcomes, the overall effectiveness of these treatments remained limited, and phototherapy was recommended for highly motivated patients. The author concluded that phototherapy could be a viable option for certain patients, although the pathophysiology of AA was still not fully understood.
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