Effectiveness of 308-nm Excimer Laser Therapy in Treating Alopecia Areata by Examining Treated Sides of Selected Alopecic Patches

January 2015 in “ Dermatology ”

Ji Won Byun, Jong Hyuk Moon, Chan Yl Bang, Jeonghyun Shin, Gwang Seong Choi

308-nm excimer laser alopecia areata hair count hair diameter phototrichogram excimer laser AA

Studysummary This study found that 308-nm excimer laser therapy improved hair diameter in alopecia areata patients, as shown by photographic assessments and a side-by-side comparison with control patches.

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The study investigated the effectiveness of 308-nm excimer laser therapy on alopecia areata (AA) by treating one side of an alopecic patch in 10 patients over 12 weeks. Results showed objective improvements in hair count and diameter on the treated side, with a significant increase in hair diameter compared to the control side. The findings indicated that 308-nm excimer laser therapy had a therapeutic effect on AA, as confirmed by photographic and phototrichogram analyses.

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Research cited in this study

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research Alopecia Areata Update

244 citations , January 2010 in “Journal of the American Academy of Dermatology”

This review discusses treatment options for alopecia areata and suggests tailored treatment plans, noting the challenges posed by spontaneous remission and limited high-quality clinical trials.

research Alopecia Areata Update

391 citations , January 2010 in “Journal of The American Academy of Dermatology”

This article reviews the clinical presentation and histopathologic features of alopecia areata and proposes a hypothesis for its development, but it reports no new clinical results.

research 308-nm Excimer Laser for the Treatment of Alopecia Areata in Children

79 citations , September 2009 in “Pediatric dermatology”

This study found that the 308-nm Excimer laser was effective and safe for treating patchy alopecia areata in children, with hair regrowth observed in 60% of treated scalp patches.

research 308-Nm Excimer Laser Therapy in Alopecia Areata

85 citations , November 2004 in “Journal of the American Academy of Dermatology”

The 308-nm excimer laser helps hair regrowth in some alopecia areata cases but not all.

research Transient CD44 Variant Isoform Expression and Reduction in CD4+/CD25+ Regulatory T Cells in C3H/HeJ Mice with Alopecia Areata

77 citations , June 2002 in “Journal of Investigative Dermatology”

CD44 variant changes start alopecia areata, but don't maintain it.

research Experimental Induction of Alopecia Areata-Like Hair Loss in C3H/HeJ Mice Using Full-Thickness Skin Grafts

131 citations , November 1998 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study observed that alopecia areata can be induced and serially transferred in C3H/HeJ mice using skin grafts, providing a useful model for studying the disease in humans.